文章标题：Hypomethylated gene RAC3 induces cell proliferation and invasion by increasing FASN expression in endometrial cancer
影响因子：5.652
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
作者列表：Cai Meijuan, Liu Fang, Fang Min, Wang Qian
发表时间：2022-7-30
DOI:10.1016/j.biocel.2022.106274
主要研究成果：Abstract
Background
Endometrial cancer (EC) is one of the most prevalent gynecological cancers with a 5-year survival rate of 20–60%. Feasible prognostic molecular biomarkers of EC are necessary for accurate prediction of EC prognosis.
Methods
RAC3 is a member of the Rho GTPases. Public databases including Gene Expression Profiling Interactive Analysis (GEPIA2), Tumor Immune Estimation Resource (TIMER), LinkedOmics, Search Tool for the Retrieval of Interacting Genes/Proteins (STRING), TISIDB and cBioPortal were employed to analyze the differential expression, clinicopathologic characteristics, functional networks, immune cell infiltrates and genetic alteration of RAC3 in EC patients.
