文章标题：Altered metabolic profiles and targets relevant to the protective effect of acteoside on diabetic nephropathy in db/db mice based on metabolomics and network pharmacology studies
影响因子：5.4
期刊：JOURNAL OF ETHNOPHARMACOLOGY
作者列表：Wenya Gao, Shuangrong Gao, Yan Zhang, Mengxiao Wang, Yuyang Liu, Tao Li, Chang Gao, Yanyan Zhou, Baolin Bian, Hongjie Wang, Xiaolu Wei, Takashi Sato, Nan Si, Wei Zhao, Haiyu Zhao
发表时间：2023-8-22
DOI:10.1007/s40618-022-01998-x
主要研究成果：Abstract
Ethnopharmacological relevance
Diabetic nephropathy (DN) was a major cause of end-stage renal failure and a common microvascular complication in patients with diabetes mellitus (DM). Acteoside (ACT) was the main ingredient extracted from the leaves of Rehmannia glutinosa, which had the functions of entering the lung, moisturizing the skin and relieving itching, nourishing yin and tonifying the kidney, cooling blood, and stopping bleeding. ACT had attracted worldwide interest because of its therapeutic effects on DM and its complications.
Aim of the study
To clarify the metabolic profiles and targets of ACT in db/db mice based on metabolomics and network pharmacology studies.
