陕西中质标品医药科技有限公司

SAFETY DATA SHEETS According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition Version: 1.0 Creation Date: Feb. 6, 2018 Revision Date: Feb. 6, 2018 1. 1.1 1.2 1.3 1.4 1.5 Identification GHS Product identifier Product name 4-Methoxyphenylhydrazine hydrochloride Other means of identification Product number Other names A506761 4-Methoxyphenylhydrazine HCl Recommended use of the chemical and restrictions on use Identified uses Uses advised against Supplier's details Company Address Telephone Fax Used for research and development only. no data available Sangon Biotech (Shanghai) Co., Ltd. 698 Xiangmin Road, Songjiang, Shanghai 201611, China +86-400-821-0268 / +86-800-820-1016 +86-400-821-0268 to 9 Emergency phone number Emergency phone number Service hours +86-21-57072055 Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). 2. 2.1 2.2 Hazard identification Classification of the substance or mixture Acute toxicity - Oral, Category 4 Acute toxicity - Dermal, Category 4 Skin sensitization, Category 1 Acute toxicity - Inhalation, Category 4 GHS label elements, including precautionary statements 4-Methoxyphenylhydrazine hydrochloride Page 1 of 9 Pictogram(s) Signal word Hazard statement(s) Precautionary statement(s) Prevention Response Storage Disposal 2.3 Warning H302 Harmful if swallowed H312 Harmful in contact with skin H317 May cause an allergic skin reaction H332 Harmful if inhaled P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P312 Call a POISON CENTER/doctor/…if you feel unwell. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. none P501 Dispose of contents/container to ... Other hazards which do not result in classification no data available 3. 3.1 Composition/information on ingredients Substances 4-Methoxyphenylhydrazine hydrochloride Page 2 of 9 ≥98% Chemical name Common names and synonyms CAS number 4-methoxyphenylhydrazine hydrochloride 4-Methoxyphenylhydrazine hydrochloride EC number Concentration 19501 58-7 4. 4.1 First-aid measures Description of necessary first-aid measures General advice 243 115-3 Medical attention is required. Consult a doctor. Show this safety data sheet (SDS) to the doctor in attendance. If inhaled Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical. Following skin contact Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor. Following eye contact Rinse with pure water for at least 15 minutes. Consult a doctor. Following ingestion Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately. 4.2 4.3 Most important symptoms/effects, acute and delayed no data available Indication of immediate medical attention and special treatment needed, if necessary no data available 5. 5.1 5.2 5.3 Fire-fighting measures Extinguishing media Suitable extinguishing media Use dry chemical, carbon dioxide or alcohol-resistant foam. Specific hazards arising from the chemical no data available Special protective actions for fire-fighters Wear self-contained breathing apparatus for firefighting if necessary. 6. Accidental release measures Page 3 of 9 4-Methoxyphenylhydrazine hydrochloride 6.1 Personal precautions, protective equipment and emergency procedures Avoid dust formation. Avoid breathing mist, gas or vapours. Avoid contacting with skin and eye. Use personal protective equipment. Wear chemical impermeable gloves. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. 6.2 6.3 Environmental precautions Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations. 7. 7.1 7.2 Handling and storage Precautions for safe handling Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam. Conditions for safe storage, including any incompatibilities Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials. 8. 8.1 8.2 8.3 Exposure controls/personal protection Control parameters Occupational Exposure limit values no data available Appropriate engineering controls Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area. Individual protection measures, such as personal protective equipment (PPE) Eye/face protection Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US). Skin protection Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator. 4-Methoxyphenylhydrazine hydrochloride Page 4 of 9 Thermal hazards no data available 9. Physical and chemical properties Physical state Colour Odour Melting point/ freezing point Boiling point or initial boiling point and boiling range Flammability Lower and upper explosion limit / flammability limit Flash point Auto-ignition temperature Decomposition temperature pH Kinematic viscosity Solubility Partition coefficient n octanol/water Vapour pressure Density and/or relative density Solid. no data available 160-162ºC (dec.) 263.5ºC at 760 mmHg no data available no data available 113.2ºC no data available no data available no data available no data available In water: soluble no data available 0.0103mmHg at 25°C 1.15g/cm3 Relative vapour density no data available Particle characteristics no data available 10. 10.1 10.2 10.3 10.4 10.5 10.6 Stability and reactivity Reactivity no data available Chemical stability no data available Possibility of hazardous reactions no data available Conditions to avoid no data available Incompatible materials no data available Hazardous decomposition products no data available Page 5 of 9 4-Methoxyphenylhydrazine hydrochloride 11. Toxicological information Acute toxicity Oral: no data available Inhalation: no data available Dermal: no data available Skin corrosion/irritation no data available Serious eye damage/irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity no data available Carcinogenicity no data available Reproductive toxicity no data available STOT-single exposure no data available STOT-repeated exposure no data available Aspiration hazard no data available 12. 12.1 12.2 12.3 12.4 Ecological information Toxicity Toxicity to fish: no data available Toxicity to daphnia and other aquatic invertebrates: no data available Toxicity to algae: no data available Toxicity to microorganisms: no data available Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil Page 6 of 9 4-Methoxyphenylhydrazine hydrochloride 12.5 no data available Other adverse effects no data available 13. 13.1 Disposal considerations Disposal methods Product The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems. Contaminated packaging Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials. 14. 14.1 14.2 14.3 14.4 14.5 14.6 14.7 Transport information UN Number ADR/RID: UN2811 UN Proper Shipping Name IMDG: UN2811 ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. IMDG: TOXIC SOLID, ORGANIC, N.O.S. IATA: TOXIC SOLID, ORGANIC, N.O.S. Transport hazard class(es) ADR/RID: 6.1 Packing group, if applicable ADR/RID: III Environmental hazards ADR/RID: no Special precautions for user no data available IATA: UN2811 IMDG: 6.1 IMDG: III IMDG: no IATA: 6.1 IATA: III IATA: no Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code no data available 15. 15.1 Regulatory information Safety, health and environmental regulations specific for the product in question 4-Methoxyphenylhydrazine hydrochloride Page 7 of 9 16. Chemical name Common names and synonyms CAS number EC number 4-methoxyphenylhydrazine hydrochloride 4-Methoxyphenylhydrazine hydrochloride 19501-58 7 243-115-3 European Inventory of Existing Commercial Chemical Substances (EINECS) Listed. EC Inventory Listed. United States Toxic Substances Control Act (TSCA) Inventory Not Listed. China Catalog of Hazardous chemicals 2015 Not Listed. New Zealand Inventory of Chemicals (NZIoC) Listed. Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed. Vietnam National Chemical Inventory Not Listed. Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Not Listed. Other information Information on revision Creation Date Feb. 6, 2018 Revision Date Feb. 6, 2018 Abbreviations and acronyms CAS: Chemical Abstracts Service ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road RID: Regulation concerning the International Carriage of Dangerous Goods by Rail IMDG: International Maritime Dangerous Goods IATA: International Air Transportation Association TWA: Time Weighted Average STEL: Short term exposure limit LC50: Lethal Concentration 50% LD50: Lethal Dose 50% EC50: Effective Concentration 50% References IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/ eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index? pageID=0&request_locale=en CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp ERG - Emergency Response Guidebook by U.S. Department of Transportation, 4-Methoxyphenylhydrazine hydrochloride Page 8 of 9 website: http://www.phmsa.dot.gov/hazmat/library/erg Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp ECHA - European Chemicals Agency, website: https://echa.europa.eu/ Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product. 4-Methoxyphenylhydrazine hydrochloride