组蛋白分类

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类型分子量结构特征功能

H2A

~14 kDa

含C端延伸

与H2B形成二聚体，稳定核小体结构

H2B

~14 kDa

高度保守

参与DNA缠绕（约147 bp）

H3

~17 kDa

含组蛋白折叠域

与H4形成四聚体，构成核小体核心

H4

~11 kDa

最保守的组蛋白

参与组蛋白八聚体组装

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靶标产品货号产品名称反应种属应用

Histone H2A相关抗体：

Histone H2A

APRab12055

Histone H2A Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA

Histone H2A

AMRe21481

Histone H2A Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,IF,IP,ELISA,CHIP,Cut&Tag

Histone H2B相关抗体：

Histone H2B

AMRe21413

Histone H2B Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,IF,IP,ELISA,CHIP,Cut&Tag

Histone H2B

APRab12063

Histone H2B Rabbit Polyclonal Antibody

Human,Mouse,Monkey

WB,IHC,ICC/IF,ELISA

Histone H2B

AMM03592

Histone H2B (7E2) Mouse Monoclonal Antibody

Human,Mouse,Rat

WB,IHC

Histone H2B

AMM86158

Histone H2B Mouse Monoclonal Antibody

Human,Mouse,Rat

WB,ICC

Histone H3相关抗体：

Histone H3

AMRe83882

Histone H3 Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC,FC

Histone H3

AMM03599

Histone H3 (Zebrafish Specific) (2C4) Mouse Monoclonal Antibody

Human,Mouse,Rat,Zebrafish

WB

Histone H3

AMRe21336

Histone H3 Rabbit Monoclonal Antibody

Human,Mouse,Rat,Cat

WB,IHC,IF,IP,ELISA,CHIP,Cut&Tag

Histone H4相关抗体：

Histone H4

APRab03394

Histone H4 Rabbit Polyclonal Antibody

Human,Mouse,Rat,Monkey

WB,IHC,ICC/IF,ELISA

Histone H4

AMRe21614

Histone H4 Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,IF,IP,ELISA,CHIP,Cut&Tag

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类型分子量结构特征功能

H1

~20-22 kDa

球状结构域+柔性C端尾巴

结合核小体进出口DNA（约20 bp），促进30 nm染色质纤维折叠及高级结构形成

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靶标产品货号产品名称反应种属应用

Histone H1

APRab00543

Histone H1 Rabbit Polyclonal Antibody

Human,Mouse

WB,IHC,ICC/IF,ELISA

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▲

变体名称表达模式定位/功能

H2A.X

组成型表达

全基因组分布；DNA损伤时C端SQE基序磷酸化（γ-H2AX），招募修复因子

H2A.Z

组成型表达

转录启动子、增强子、异染色质边界，促进转录激活与抑制双重功能

macroH2A

组织特异性

雌性哺乳动物失活X染色体（Barr小体）；抑制转录

H2A.Bbd

睾丸特异

转录活跃染色质；降低核小体稳定性

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靶标产品货号产品名称反应种属应用

Histone H2A.X

AMRe12056

Histone H2A.X (13P7) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,FC,IP

Histone H2A.Z

APRab12060

Histone H2A.Z Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ELISA

Histone H2A.Z

AMRe12059

Histone H2A.Z (17I8) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,FC

MACROH2A2

AMM83434

MACROH2A2 Mouse Monoclonal Antibody

Human

IHC

macroH2A.1

AMRe13549

macroH2A.1 (2T18) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

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变体名称表达模式定位/功能

H3.1

RD型，CAF-1复合体介导

复制偶联的染色质组装

H3.2

RD型

功能类似H3.1，表达略不同

H3.3

RI型，HIRA/ATRX/DAXX介导

转录活跃区、端粒、着丝粒；与H3.1仅4-5个氨基酸差异但功能迥异

CENP-A

RI型，HJURP介导

着丝粒身份决定因子；替代H3形成特殊核小体，招募动粒蛋白

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靶标恩玑货号产品名称反应种属应用

Histone H3.3

APRab12071

Histone H3.3 Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA

Histone H3.3

APRab00058

Histone H3.3 Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

Histone H3.3

AMRe85655

Histone H3.3 Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC

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▲

变体名称表达模式定位/功能

H1.0

终末分化细胞富集

促进染色质高度凝聚

H1.1-H1.5

体细胞表达

维持染色质基本结构

H1t

睾丸特异

精子发生期染色质重塑

H1oo

卵母细胞特异

早期胚胎发育

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靶标恩玑货号产品名称反应种属应用

Histone H1.0

AMRe12052

Histone H1.0 (10F13) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

Histone H1.2

AMRe02083

Histone H1.2 Rabbit Monoclonal antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

Histone H1.3

AMRe02084

Histone H1.3 Rabbit Monoclonal antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

Phospho-HistoneH1.4(T17)

AMRe83776

Phospho-HistoneH1.4(T17) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC

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修饰类型示例

单甲基化（Mono Methyl）：me1

H3K4me1

二甲基化（Di Methyl）：me2

H3K4me2

三甲基化（Tri Methyl）：me3

H3K4me3

乙酰化（Ac）

H3K9ac、H3K27ac、H4K16ac

磷酸化（p）

H3S10ph

泛素化（Ub）

H2AK119ub

其他修饰

瓜氨酸化、乳酸化、巴豆酰化

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▲

靶标产品货号产品名称反应种属应用

单甲基化修饰相关抗体：

Histone H2A(mono methyl K118)

AMRe84153

Histone H2A(mono methyl K118) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC

Histone H2B(mono methylK116)

AMRe84635

Histone H2B(mono methylK116) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC

Mono Methyl-Histone H2B (Arg79)

AMRe04022

Mono Methyl-Histone H2B (Arg79) Rabbit Monoclonal Antibody

Human

WB

Histone H3 (Mono Methyl Lys37)

APRab06135

Histone H3 (Mono Methyl Lys37) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA

Histone H3 (Mono Methyl Lys5)

APRab06136

Histone H3 (Mono Methyl Lys5) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA

Histone H3(mono methyl K14)

AMRe84518

Histone H3(mono methyl K14) Rabbit Monoclonal Antibody

Human,Mouse

WB,ICC,FC

Mono Methyl-Histone H3 (Lys18)

AMRe03281

Mono Methyl-Histone H3 (Lys18) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB

Histone H3 (Mono Methyl Lys10)

APRab06134

Histone H3 (Mono Methyl Lys10) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ELISA

Histone H3 (Mono Methyl Lys80)

APRab06137

Histone H3 (Mono Methyl Lys80) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ELISA

Mono Methyl-Histone H3 (Arg2)

AMRe04012

Mono Methyl-Histone H3 (Arg2) Rabbit Monoclonal Antibody

Human, Mouse

WB,ICC/IF

Mono Methyl-Histone H3 (Lys36)

AMRe03954

Mono Methyl-Histone H3 (Lys36) Rabbit Monoclonal Antibody

Human, Mouse, Rat

WB,ICC/IF

Mono Methyl-Histone H3 (Lys9)

AMRe03910

Mono Methyl-Histone H3 (Lys9) Rabbit Monoclonal Antibody

Human, Mouse, Rat

WB,IHC,ICC/IF

Histone H3 (Mono Methyl Lys4)

AMRe21105

Histone H3 (Mono Methyl Lys4) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA,IP

Mono Methyl-Histone H4 (Lys20)

AMRe03937

Mono Methyl-Histone H4 (Lys20) Rabbit Monoclonal Antibody

Human, Mouse, Rat

WB,IHC,ICC/IF

Mono/Di/TriMethyl-Histone H3 (Lys79)

AMRe03999

Mono/Di/TriMethyl-Histone H3 (Lys79) Rabbit Monoclonal Antibody

Human, Mouse, Rat

WB,IHC

二甲基化修饰相关抗体：

DiMethyl-Histone H3 (Lys27)

AMM03581

DiMethyl-Histone H3 (Lys27) (5F6) Mouse Monoclonal Antibody

Human,Mouse,Rat

WB,ICC/IF,IP

Histone H3 (Di Methyl Lys10)

APRab06125

Histone H3 (Di Methyl Lys10) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA

Histone H3 (Di Methyl Lys5)

APRab06130

Histone H3 (Di Methyl Lys5) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA

DiMethyl-Histone H3 (Lys4)

APRab00675

DiMethyl-Histone H3 (Lys4) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,FC,IP,ChIP

Histone H3 (Di-Methyl-K80)

APRab06133

Histone H3 (Di-Methyl-K80) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB

DiMethyl-Histone H3 (Lys36)

AMRe03906

DiMethyl-Histone H3 (Lys36) Rabbit Monoclonal Antibody

Human, Mouse, Rat

WB,IHC,ICC/IF

DiMethyl-Histone H3 (Lys79)

AMRe03979

DiMethyl-Histone H3 (Lys79) Rabbit Monoclonal Antibody

Human, Mouse, Rat

WB,IHC,ICC/IF

Histone H3 (Di Methyl Lys9)

AMRe21084

Histone H3 (Di Methyl Lys9) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA,IP

三甲基化修饰相关抗体：

Histone H3(Tri Methyl Lys79)

AMM06155

Histone H3(Tri Methyl Lys79)(3G3)Mouse Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,IP

Histone H3 (Tri Methyl Lys4)

AMRe21106

Histone H3 (Tri Methyl Lys4) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA,IP

Histone H3(Tri Methyl Lys36)

AMM06152

Histone H3(Tri Methyl Lys36)(Q12)Mouse Monoclonal Antibody

Human,Mouse,Rat

WB

Histone H3 (Tri-Methyl-K5)

APRab06144

Histone H3 (Tri-Methyl-K5) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ELISA

Tri-Methyl-Histone H3 (K10)

APRab04156

Tri-Methyl-Histone H3 (K10) Rabbit Polyclonal Antibody

Human,Rat,Mouse

WB,ELISA

Tri Methyl-Histone H3 (Lys14)

APRab00850

Tri Methyl-Histone H3 (Lys14) Rabbit Polyclonal Antibody

Human,Rat

WB

Histone H3 (Tri Methyl Lys27)

AMRe21116

Histone H3 (Tri Methyl Lys27) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ELISA,IP

Tri Methyl-Histone H3 (Lys9)

AMRe87560

Tri Methyl-Histone H3 (Lys9) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

乙酰化修饰相关抗体：

Histone H4 (Acetyl Lys16)

APRab06213

Histone H4 (Acetyl Lys16) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

Histone H4 (Acetyl Lys12)

APRab06212

Histone H4 (Acetyl Lys12) Rabbit Polyclonal Antibody

Human,Mouse,Rat,Monkey

WB,IHC,ICC/IF,ELISA

Histone H4 (Acetyl Lys5)

APRab06215

Histone H4 (Acetyl Lys5) Rabbit Polyclonal Antibody

Human,Mouse,Rat,Monkey

WB,IHC,ICC/IF,ELISA

Histone H2B (Acetyl Lys15)

APRab06196

Histone H2B (Acetyl Lys15) Rabbit Polyclonal Antibody

Human,Mouse

WB,IHC,ICC/IF,ELISA

Histone H4 (Acetyl Lys8)

APRab06216

Histone H4 (Acetyl Lys8) Rabbit Polyclonal Antibody

Human,Mouse,Rat,Monkey

WB,IHC,ICC/IF,ELISA

Histone H3 (Acetyl Lys27)

APRab06206

Histone H3 (Acetyl Lys27) Rabbit Polyclonal Antibody

Human,Mouse,Rat,Monkey,Arabidopsis thaliana

WB,IHC,ICC/IF,ELISA,IP

Acetyl-Histone H4 (Lys5)

AMRe03268

Acetyl-Histone H4 (Lys5) Rabbit Monoclonal Antibody

Human,Mouse

WB,IHC,ICC/IF,IP

Histone H2B (Acetyl Lys126)

APRab06195

Histone H2B (Acetyl Lys126) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ELISA

Acetyl-Histone H3 (Lys4)

AMRe03275

Acetyl-Histone H3 (Lys4) Rabbit Monoclonal Antibody

Human,Mouse

WB,ICC/IF

Acetyl-HistoneH3(LYs9)

AMRe84307

Acetyl-HistoneH3(LYs9) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC,FC,IP

Acetyl-Histone H3(Lys18)

AMRe84527

Acetyl-Histone H3(Lys18) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC,FC,IP

Acetyl-Histone H3(Lys23)

AMRe84536

Acetyl-Histone H3(Lys23) Rabbit Monoclonal Antibody

Human,Mouse

WB,ICC,IP

Acetyl Histone H1 (K25)

APRab04160

Acetyl Histone H1 (K25) Rabbit Polyclonal Antibody

Human,Monkey

WB,IHC,ICC/IF,ELISA

Histone H3 (Acetyl Lys14)

APRab06202

Histone H3 (Acetyl Lys14) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ICC/IF,ELISA

Histone H3 (Acetyl Lys123)

APRab06200

Histone H3 (Acetyl Lys123) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ELISA

Acetyl-Histone H2B (Lys20)

APRab00701

Acetyl-Histone H2B (Lys20) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,FC,IP,ChIP

Histone H2B (Acetyl Lys21)

APRab06197

Histone H2B (Acetyl Lys21) Rabbit Polyclonal Antibody

Human,Rat,Mouse

WB,ELISA

Acetyl-Histone H4 (Lys16)

APRab00849

Acetyl-Histone H4 (Lys16) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

磷酸化修饰相关抗体：

Phospho-Histone H3 (Ser10/Thr11)

AMRe03296

Phospho-Histone H3 (Ser10/Thr11) Rabbit Monoclonal antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,IP

Phospho-HistoneH3(S10)

AMRe83712

Phospho-HistoneH3(S10) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC,IP

Phospho-Histone H2A.X (Ser139)

AMM03680

Phospho-Histone H2A.X (Ser139) (7G9) Mouse Monoclonal Antibody

Human,Mouse

WB,ICC/IF

Phospho-Histone H3 (Ser28)

AMRe02090

Phospho-Histone H3 (Ser28) Rabbit Monoclonal Antibody

Human,Mouse

WB,IHC,ICC/IF

Phospho-HistoneH1.4(T17)

AMRe83776

Phospho-HistoneH1.4(T17) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC

Phospho-Histone H2A.X (Ser139)

AMRe03773

Phospho-Histone H2A.X (Ser139) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IP

Phospho-Histone H3 (Thr3)

AMRe03284

Phospho-Histone H3 (Thr3) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,ICC/IF

Phospho-Histone H2A (Ser129)

APRab00687

Phospho-Histone H2A (Ser129) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB

Phospho-Histone H4 (Ser1)

APRab00852

Phospho-Histone H4 (Ser1) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,IHC

Phospho-HistoneH2B(T129)

AMRe83770

Phospho-HistoneH2B(T129) Rabbit Monoclonal Antibody

Yeast

WB

Histone H3 (Phospho Thr3)

AMRe21090

Histone H3 (Phospho Thr3) Rabbit Monoclonal Antibody

Human

WB,IHC,IF,IP,ELISA,CHIP,Cut&Tag

其他修饰相关抗体：

Histone deacetylase 9

APRab12050

Histone deacetylase 9 Rabbit Polyclonal Antibody

Human,Rat,Mouse

WB,IHC,ICC/IF,ELISA

Histone deacetylase 7a

APRab12049

Histone deacetylase 7a Rabbit Polyclonal Antibody

Human,Mouse

WB,IHC,ICC/IF,ELISA

Histone deacetylase 6

APRab12048

Histone deacetylase 6 Rabbit Polyclonal Antibody

Human,Mouse

WB,IHC,ICC/IF,ELISA

Histone deacetylase 10

APRab12047

Histone deacetylase 10 Rabbit Polyclonal Antibody

Human,Mouse,Rat,Monkey

WB,IHC,ICC/IF,ELISA

Histone H2B(crotonylK12)

AMRe84162

Histone H2B(crotonylK12) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF,ICC

Histone H2B(formyl K116)

AMRe84155

Histone H2B(formyl K116) Rabbit Monoclonal Antibody

Human,Mouse

WB,ICC

Histone H2B(formyl K108)

AMRe84632

Histone H2B(formyl K108) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC

Histone H3(symmetricdimethylR17)

AMRe84144

Histone H3(symmetricdimethylR17) Rabbit Monoclonal Antibody

Human,Mouse

WB,ICC

Crotonyl-Histone H2B (Lys12)

AMRe03903

Crotonyl-Histone H2B (Lys12) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

Crotonyl-Histone H2B (Lys12)

AMRe87546

Crotonyl-Histone H2B (Lys12) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

Formyl-Histone H3

AMRe86229

Formyl-Histone H3 (Lys122) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC

Histone H3(formylK122)

AMRe84637

Histone H3(formylK122) Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC

Histone H3(mutated K27Met)

AMRe84538

Histone H3(mutated K27Met) Rabbit Monoclonal Antibody

Human

WB,ICC,IP

Histone H3 (Citrulline R2+R8+R17)

APRab00455

Histone H3 (Citrulline R2+R8+R17) Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB