橄榄苦甙 (Oleuropein) 长沙上禾生物中英文简介

产品名称

橄榄苦甙

Oleuropein

化学描述

一种天然裂环烯醚萜苷，是油橄榄叶和果实中主要的苦味多酚化合物，也是地中海饮食健康益处的关键活性成分之一。

A natural secoiridoid glycoside, the principal bitter phenolic compound in olive leaves and fruits, and a key bioactive component contributing to the health benefits of the Mediterranean diet.

核心成分

橄榄苦甙 (Oleuropein)

Oleuropein

植物来源

木犀科植物油橄榄 (Olea europaeaL.) 的干燥叶片及未成熟果实

Dried leaves and unripe fruits of Olea europaeaL. (Oleaceae family)

外观性状

白色至淡黄色结晶性粉末 (高纯单体)；或棕黄色至浅棕色精细粉末 (标准化提取物)。味极苦。

White to pale yellow crystalline powder (high purity monomer); or brownish-yellow to light brown fine powder (standardized extract). Extremely bitter taste.

主要规格

高纯单体：HPLC ≥98%, ≥95% (医药/科研级)
标准化提取物 (橄榄叶提取物)：
- 橄榄苦甙 6%, 10%, 20%, 40%, 60%, 80% (HPLC)
- 羟基酪醇 ≥2%, ≥5% (水解后产物，HPLC)
常规提取物：4:1, 10:1 (TLC)

High Purity Monomer: HPLC ≥98%, ≥95% (Pharma/Research Grade)
Standardized Extract (Olive Leaf Extract):
- Oleuropein 6%, 10%, 20%, 40%, 60%, 80% (HPLC)
- Hydroxytyrosol ≥2%, ≥5% (hydrolyzed product, HPLC)
Conventional Extract: 4:1, 10:1 (TLC)

检测方法

HPLC, TLC, UV

HPLC, TLC, UV

CAS No.

32619-42-4

32619-42-4

分子式

C₂₅H₃₂O₁₃

C₂₅H₃₂O₁₃

分子量

540.52

540.52

药理功效

1. 强效抗氧化与抗炎 (Potent Antioxidant & Anti-inflammatory)：核心基础功效。清除自由基能力极强，抑制NF-κB、COX-2、LOX等炎症通路，减轻全身慢性低度炎症，是预防多种慢性病的基石。
2. 心血管保护 (Cardiovascular Protection)：降低血压（血管紧张素转换酶抑制剂活性），扩张血管，改善内皮功能，抗动脉粥样硬化，降低低密度脂蛋白(LDL)氧化。
3. 降血糖与改善胰岛素抵抗 (Hypoglycemic & Improves Insulin Resistance)：增强胰岛素敏感性，促进葡萄糖摄取，保护胰腺β细胞。
4. 抗菌、抗病毒、抗真菌 (Antibacterial, Antiviral, Antifungal)：广谱抗微生物活性，对耐药菌也有效，抗流感病毒、疱疹病毒、HIV等。
5. 神经保护 (Neuroprotective)：可穿过血脑屏障，减轻神经炎症和氧化应激，对阿尔茨海默病、帕金森病有潜在益处。
6. 抗肿瘤 (Antitumor)：诱导癌细胞凋亡，抑制肿瘤血管生成。
7. 增强免疫力 (Enhances Immunity)。

1. Potent Antioxidant & Anti-inflammatory: Core foundational function. Extremely strong free radical scavenging ability, inhibits inflammatory pathways (NF-κB, COX-2, LOX), reduces systemic chronic low-grade inflammation, foundational for preventing various chronic diseases.
2. Cardiovascular Protection: Lowers blood pressure (ACE inhibitor activity), vasodilates, improves endothelial function, anti-atherosclerotic, reduces LDL oxidation.
3. Hypoglycemic & Improves Insulin Resistance: Enhances insulin sensitivity, promotes glucose uptake, protects pancreatic β-cells.
4. Antibacterial, Antiviral, Antifungal: Broad-spectrum antimicrobial activity, effective against drug-resistant strains, active against influenza virus, herpes virus, HIV, etc.
5. Neuroprotective: Can cross the blood-brain barrier, reduces neuroinflammation and oxidative stress, potential benefits for Alzheimer's and Parkinson's diseases.
6. Antitumor: Induces cancer cell apoptosis, inhibits tumor angiogenesis.
7. Enhances Immunity.

应用领域

保健品/功能性食品：“三高” (高血压、高血糖、高血脂) 综合调理产品、心血管健康胶囊、抗衰老与抗氧化补充剂、增强免疫力产品、代谢综合征管理产品。
医药：心血管疾病、糖尿病、神经退行性疾病、感染性疾病的辅助治疗或药物研发候选成分。
化妆品：顶级抗衰老精华/面霜（对抗光老化、氧化损伤、炎症衰老）、抗炎舒缓产品（敏感肌、痘痘肌）、天然防腐剂（替代化学防腐剂）。
功能性食品：特级初榨橄榄油强化剂、健康饮品。
饲料添加剂：替抗（替代抗生素），提高畜禽抗病力和肉质。

Health Products/Functional Food: Comprehensive management products for "Three Highs" (hypertension, hyperglycemia, hyperlipidemia), cardiovascular health capsules, anti-aging and antioxidant supplements, immune-boosting products, metabolic syndrome management products.
Pharma: Candidate or adjuvant for cardiovascular diseases, diabetes, neurodegenerative diseases, infectious diseases.
Cosmetics: Premium anti-aging serums/creams (combats photoaging, oxidative damage, inflammaging), anti-inflammatory soothing products (sensitive skin, acne-prone skin), natural preservative (replaces chemical preservatives).
Functional Food: Fortifier for extra virgin olive oil, health beverages.
Feed Additive: Antibiotic replacement, improves disease resistance and meat quality in livestock and poultry.

包装储存

内双层铝箔袋，外纸板桶（1kg/袋，25kg/桶）。
密封，避光，阴凉干燥处，建议2-8°C冷藏保存。保质期2年。

Inner double-layer aluminum foil bag, outer cardboard drum (1kg/bag, 25kg/drum).
Sealed, stored in a cool, dry place away from light. Refrigeration at 2-8°C is recommended. Shelf life 2 years.