Supplier Product Identification Physical and Chemical Properties First Aid Measures Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-. carbazole-9-propanoic acid > 3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-. carbazole-9-propanoic acid(116649-85-5)

3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-. carbazole-9-propanoic acid(116649-85-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-. carbazole-9-propanoic acid
Synonyms
3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
9H-Carbazole-9-propanoic acid, 3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-, (R)-
CAS
116649-85-5
Formula
C21H21FN2O4S
Molecular Weight
416.47
Merck
12,10455

Physical and Chemical Properties

Appearance
Crystalline solid.
Solubility in water
0.5 g/L (25 C)
Vapor Pressure
4.9E-18 (25 C)
Density
1.43 g/cm3
pKa/pKb
4.60 (pKa)
Partition Coefficient
4.09
Usage
A thromboxane receptor antagonist indicated for the treatment of coronary artery disease. It has also been used for the treatment of asthma.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Never give anything by mouth to an unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.
Inhalation
If inhaled remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel. Get immediate medical attention.
Skin
In case of skin contact, immediately wash skin with soap and plenty of water. Remove contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
Eyes
In case of contact with eyes, hold eyelids apart and flush eyes with plenty of water. After initial flushings, remove any contact lenses and continue flushing for at least 20 minutes. Have eyes examined and tested by medical personnel.

Exposure Controls/Personal Protection

Personal Protection
Wear a NIOSH/MSHA approved self-contained breathing apparatus and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Exposure Effects
May be harmful by inhalation, ingestion, or skin absorption. May cause eye, skin, or respiratory system irritation. The toxicological properties of this compound have not been fully evaluated.

Fire Fighting Measures

Fire Fighting
Wear self-contained breathing apparatus pressure-demand (MSHA/NIOSH approved or equivalent), and full protective gear to prevent contact with skin and eyes. Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray when fighting fires involving this material.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place in disposal container. Avoid raising dust. After removal, ventilate contaminated area and flush thoroughly with water.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
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