Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Amoxapine(14028-44-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Amoxapine
Synonyms
2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine
8-Chloro-6-piperazin-1-ylbenzo[b][1,5]benzoxazepine
Amoxan
Asendin
Moxadil
CAS
14028-44-5
Formula
C17H16ClN3O
Molecular Weight
313.79000000000002
EINECS
237-867-1
RTECS
HQ4025500
RTECS Class
Drug; Human Data
Merck
12,616
Beilstein/Gmelin
832057
Beilstein Reference
6-27

Physical and Chemical Properties

Appearance
White solid
Solubility in water
Insoluble
Melting Point
175 - 176
Boiling Point
470
Vapor Pressure
5E-9 (25 C)
pKa/pKb
5.97 (pKb)
Heat Of Vaporization
73.2 kJ/mol
Usage
Tricyclic antidepressant.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed.

Hazards Identification

Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
Harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
22
EC Safety Phrase
36

Exposure Controls/Personal Protection

Personal Protection
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
Exposure Effects
Harmful if swallowed. Calif. Prop. 65 reproductive hazard. Target organ(s): Heart. Central nervous system.

Fire Fighting Measures

Flash Point
238
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
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