Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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Salicylamide(65-45-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
Salicylamide
Synonyms
2-Carboxamidophenol
2H-Pyran-2-acetic acid, alpha-ethyl-6-(5-(2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro(4.1.5.3)pentadec-13-en-9-yl)-2-hydroxy-1,3-dimethyl-4-oxoheptyl)tetrahydro-3,5-dimethyl-
2-Hydroxybenzamide
A-28086A
Algamon
Antibiotic A 28086 factor A
Antibiotic A 28086A
Antibiotic C 7819B
C-7819B
Oramid
Salicylic acid amide
Urtosal
CAS
55134-13-9
CAS
65-45-2
Formula
C43H72O11
Formula
C7H7NO2
Molecular Weight
765.04
Molecular Weight
137.13999999999999
EINECS
200-609-3
RTECS
VN6475000
RTECS
VO8640000
RTECS Class
Drug; Reproductive Effector; Primary Irritant
Merck
12,6506
Merck
12,8480
Beilstein/Gmelin
1678311
Beilstein/Gmelin
742439
Beilstein Reference
4-10-00-00169

Physical and Chemical Properties

Appearance
White or slightly pink crystalline powder.
Solubility in water
2 g/L (20 C)
Melting Point
137
Boiling Point
318
Vapor Pressure
0.0002 (25 C)
Density
1.33 g/cm3 (20 C)
pKa/pKb
8.37 (pKa)
Partition Coefficient
1.28
Heat Of Vaporization
58.2 kJ/mol
Heat Of Combustion
-3352 kJ/mol
Usage
Antibiotic.
Usage
Medication.
Refractive Index
1.562 (20 C)

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Ingestion
May be fatal if swallowed.
Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
Eyes
May cause irritation.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Store at 2 - 8 C. Keep container tightly closed.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation
Inhalation of dust may cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
Causes eye irritation.
Ingestion
May cause irritation of the digestive tract. Overexposure may produce CNS depression, hypotension, eventually respiratory arrest, but does not produce excitement, seizures, acidosis, or hypoprothrombinemia. May be harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
R 22 36/37/38
EC Risk Phrase
28
EC Safety Phrase
28 36/37 45
EC Safety Phrase
S 22 26 36/37/39
UN (DOT)
2811

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection,
Exposure Effects
studies with animals indicate that salicylamide overdoses may produce central nervous system depression (rather than CNS stimulation sometimes seen early in salicylate poisonings.)
Exposure Effects
Target organs: heart, skeletal muscles.
Poison Class
3

Fire Fighting Measures

Flash Point
146
Fire Fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire Potential
This material is probably combustible.

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities
Acids (mineral, non-oxidizing, e.g. hydrochloric acid, hydrofluoric acid, muriatic acid, phosphoric acid), acids (mineral, oxidizing, e.g. chromic acid, hypochlorous acid, nitric acid, sulfuric acid), metals (alkali and alkaline, e.g. cesium, potassium, sodium), metals and metal compounds (toxic, e.g. beryllium, lead acetate, nickel carbonyl, tetraethyl lead), oxidizing agents (strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium nitrate), reducing agents (strong, e.g. aluminum carbide, chlorosilane, hydrogen phosphide, lithium hydride), water reactive substances (e.g. acetic anyhdride, alkyl aluminum chloride, calcium carbide, ethyl dichlorosilane).
Stability
Stable if stored as directed.
Stability
Stable under normal temperatures and pressures. May discolor on exposure to light.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Decomposition
Oxides of carbon.

Transport Information

UN Number
2811
Hazard Class
6.1
Packing Group
II
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