Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
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Etodolac(41340-25-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification

Product Identification

Product Name
Etodolac
Synonyms
1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
AY-24236
Etodolic acid
Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-
Ultradol
CAS
41340-25-4
Formula
C17H21NO3
Molecular Weight
287.36
RTECS
UQ0360000
Merck
12,3920

Physical and Chemical Properties

Solubility in water
Slightly soluble
Melting Point
145 - 148
Boiling Point
508
Vapor Pressure
3.9E-11 (25 C)
Density
1.193 g/cm3 (20 C)
pKa/pKb
4.31 (pKa)
Partition Coefficient
3.59
Heat Of Vaporization
81.8 kJ/mol
Usage
Non-steroidal anti-inflammatory drug (nsaid) - of the arylalkanoic acids sub-group - effective in treating pain and inflammation in the body.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Store at 2 - 8 C.

Exposure Controls/Personal Protection

Personal Protection
Chemical resistant gloves, safety goggles.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Exposure Effects
Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Possible teratogen. Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals. Gastrointestinal disturbances. Exposure can cause: Nausea, dizziness, and headache.

Fire Fighting Measures

Fire Fighting
EXTINGUISHING MEDIA Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, carbon dioxide, and nitrogen oxides.
Combustion Products
Emits toxic fumes under fire conditions.

Hazards Identification

EC Risk Phrase
R: 23/24/25 40
EC Safety Phrase
S: 22 36 45
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