Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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p-2-Thiazolylsulfamoylsuccinanilic acid(116-43-8)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
p-2-Thiazolylsulfamoylsuccinanilic acid
Synonyms
2-(N4-Succinylsulfanilamido)thiazole
4'-(2-Thiazolylsulfamoyl)succinanilic acid
Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
Cremosuxidine
Sulfenterone
Thiacyl
CAS
116-43-8
Formula
C13H13N3O5S2
Molecular Weight
355.4
EINECS
204-141-0
RTECS
WM4767000
RTECS Class
Drug; Natural Product
Merck
12,9046
Beilstein/Gmelin
349989
Beilstein Reference
4-27-00-04637

Physical and Chemical Properties

Solubility in water
Very soluble
Melting Point
187 - 193
pKa/pKb
4.51 (pKa)
Partition Coefficient
.74
Usage
Sulfonamid class antibiotic.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed.

Hazards Identification

Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Ingestion
May be harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
42/43
EC Safety Phrase
22 36/37 45

Exposure Controls/Personal Protection

Personal Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Exposure Effects
Harmful. May cause sensitization by inhalation and skin contact. Target organ(s): Kidneys. Blood.

Fire Fighting Measures

Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities
Oxidizing agents.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.
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