Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
Home > 2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride > 2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride(1185-53-1)

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride(1185-53-1)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
Tris (hydroxymethyl) aminomethane hydrochloride
Trizma hydrchloride
CAS
1185-53-1
Formula
C4H12ClNO3
Molecular Weight
157.6
EINECS
214-684-5
Merck
12,9902
Beilstein/Gmelin
3675235
Beilstein Reference
0-04-00-00303

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Soluble
Melting Point
149
pKa/pKb
8.1(at 25℃) (pKa)

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation
The toxicological properties of this substance have not been fully investigated. Inhalation of dust may cause respiratory tract irritation.
Skin
No information regarding skin irritation and other potential effects was found.
Eyes
No information regarding eye irritation and other potential effects was found.
Ingestion
The toxicological properties of this substance have not been fully investigated.
EC Safety Phrase
S 22 24/25

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
The toxicological properties of this substance have not been fully investigated.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Disposal Code
3
Incompatibilities
Oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Decomposition
Nitrogen oxides, bromine.

Transport Information

HS Code
2922 19 80
Contact More