Aconitine(302-27-2)
Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Accidental Release Measures
Stability and Reactivity
Transport Information
Product Identification
Product Name
Aconitine
Aconitine
Synonyms
2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine-4,8,9,11,11a(1H,7H)-pentol, 1-ethyldecahydro-6,10,13-trimethoxy-3-(methoxymethyl)-, 11a-acetate 8-benzoate
Acetylbenzoylaconine
Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1a,3a,6a,14a,15a,16b)-
Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-
2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine-4,8,9,11,11a(1H,7H)-pentol, 1-ethyldecahydro-6,10,13-trimethoxy-3-(methoxymethyl)-, 11a-acetate 8-benzoate
Acetylbenzoylaconine
Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1a,3a,6a,14a,15a,16b)-
Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-
CAS
302-27-2
302-27-2
Formula
C34H47NO11
C34H47NO11
Molecular Weight
645.75
645.75
EINECS
206-121-7
206-121-7
RTECS
AR5960000
AR5960000
RTECS Class
Human Data; Natural Product
Human Data; Natural Product
Merck
13,120
13,120
Beilstein/Gmelin
74608
74608
Beilstein Reference
5-21-06-00310
5-21-06-00310
EC Index Number
614-008-00-2
614-008-00-2
Physical and Chemical Properties
Appearance
White crystalline solid.
White crystalline solid.
Solubility in water
0.26 g/L (15 C)
0.26 g/L (15 C)
Melting Point
198 - 199
198 - 199
pKa/pKb
5.88(at 25℃) (pKa)
5.88(at 25℃) (pKa)
Usage
Neurotoxin.
Neurotoxin.
First Aid Measures
Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and Storage
Storage
Keep tightly closed.
Keep tightly closed.
Hazards Identification
Inhalation
May be fatal if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
May be fatal if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be fatal if absorbed through skin. Readily absorbed through skin.
May cause skin irritation. May be fatal if absorbed through skin. Readily absorbed through skin.
Eyes
May cause eye irritation.
May cause eye irritation.
Ingestion
May be fatal if swallowed.
May be fatal if swallowed.
Hazards
Emits toxic fumes under fire conditions.
Emits toxic fumes under fire conditions.
EC Risk Phrase
26/28
26/28
EC Safety Phrase
24 45
24 45
UN (DOT)
1544
1544
Exposure Controls/Personal Protection
Personal Protection
Compatible chemical-resistant gloves.
Compatible chemical-resistant gloves.
Respirators
Government approved respirator.
Government approved respirator.
Exposure Effects
Very toxic by inhalation, in contact with skin and if swallowed. Readily absorbed through skin. Target organ(s): Nerves. Heart.
Very toxic by inhalation, in contact with skin and if swallowed. Readily absorbed through skin. Target organ(s): Nerves. Heart.
Poison Class
1
1
Fire Fighting Measures
Fire Fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire Potential
Non-Combustible
Non-Combustible
Accidental Release Measures
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and Reactivity
Stability
Stable at normal temperatures and pressures.
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, Strong bases.
Strong oxidizing agents, Strong bases.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.
Fire may produce irritating, corrosive and/or toxic gases.
Transport Information
UN Number
1544
1544
Hazard Class
6.1
6.1
Packing Group
I
I