Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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(+)-Pilocarpine hydrochloride(54-71-7)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
(+)-Pilocarpine hydrochloride
Synonyms
2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S,4R)-
2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S-cis)-
Adsorbocarpine
Pilocarpine muriate
Pilovisc
Salagen
CAS
54-71-7
Formula
C11H17ClN2O2
Molecular Weight
244.75
EINECS
200-212-5
RTECS
TK1450000
RTECS Class
Drug; Reproductive Effector; Human Data
Beilstein/Gmelin
4034491

Physical and Chemical Properties

Appearance
odorless white to off-white crystalline powder
Melting Point
202
Usage
Miotic. Used to reduce the eye of the pupil during the treatment of glaucoma.

First Aid Measures

Ingestion
SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE. Wash mouth out with water.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container. Store protected from light.
Handling
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.

Hazards Identification

Ingestion
May be fatal if swallowed. May cause irritation of the digestive tract.
Inhalation
May be fatal if inhaled. May cause respiratory tract irritation.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Hazards
Contact with metals may evolve flammable hydrogen gas.
UN (DOT)
2811

Exposure Controls/Personal Protection

Personal Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire Potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks
Avoid runoff into storm sewers and ditches which lead to waterways. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, oxides of chlorine.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number
2811
Hazard Class
6.1
Packing Group
I; II; III
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