Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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C.I. 45350(518-47-8)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
C.I. 45350
Synonyms
9-(o-Carboxyphenyl)-6-hydroxy-3H-xanthen-3-one, disodium salt
D and C Yellow No. 8
Fluorescein sodium
Fluorin
Resorcinol phthalein sodium
Uranine
CAS
518-47-8
Formula
C20H10Na2O5
Molecular Weight
376.28
EINECS
208-253-0
RTECS
LM5425000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
Merck
13,4185
Beilstein/Gmelin
3833041
Beilstein Reference
5-19-06-00456

Physical and Chemical Properties

Appearance
Orange-red to dark red powder. Odorless and almost tasteless.
Solubility in water
500 g/L
Melting Point
> 300
Density
1.601 g/cm3 (20 C)
pKa/pKb
2.2, 4.4, 6.7(at 25℃) (pKa)
Usage
Dye, ink pigment, in cosmetic products.

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion
In high doses may cause gastric irritation, nausea, vomiting, fever, skin rashes, and blood abnormalities including anemia.
Inhalation
Inhalation of dust may cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
EC Safety Phrase
S 22 24/25

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Potential
This material is probably combustible.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.

Stability and Reactivity

Disposal Code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide, sodium oxide.

Transport Information

HS Code
3204 12 00
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