Supplier Product Identification Physical and Chemical Properties Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Troglitazone(97322-87-7)

Supplier Product Identification Physical and Chemical Properties Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Troglitazone
Synonyms
2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl) methoxy)phenyl)methyl)
5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione
CS-045
GR-92132X
Rezulin
Romglizone
CAS
97322-87-7
Formula
C24H27NO5S
Molecular Weight
441.55
RTECS
XJ5813130
Merck
12,9898
Beilstein/Gmelin
4338399

Physical and Chemical Properties

Appearance
Yellow solid.
Solubility in water
Insoluble
Melting Point
184 - 186
Vapor Pressure
7.2E-18 (25 C)
Density
1.266 g/cm3 (20 C)
pKa/pKb
6.34 (pKa)
Partition Coefficient
4.99
Usage
An anti-diabetic and antiinflammatory drug.

Handling and Storage

Storage
This product should be stored at room temperature. It should be kept in a tightly closed container.

Hazards Identification

Inhalation
Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately.
Skin
Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately.
Eyes
Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately.
Ingestion
Remove dentures and clear mouth. If person is conscious, rinse mouth with water. Call physician or poison control immediately.

Exposure Controls/Personal Protection

Personal Protection
For spill clean up, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is recommended.

Fire Fighting Measures

Fire Fighting
Extinguish with carbon dioxide, dry chemical powder, polymer foam, water spray. Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed.

Stability and Reactivity

Stability
This material is stable if stored as directed.
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