Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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Rutaecarpine(84-26-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
Rutaecarpine
Synonyms
8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
Rhetine
Rutaecarpine
CAS
84-26-4
Formula
C18H13N3O
Molecular Weight
287.32
Merck
12,8451

Physical and Chemical Properties

Appearance
White solid.
Solubility in water
26 mg/L (25 C)
Melting Point
259.5 - 260
Boiling Point
550
Vapor Pressure
3.8E-12 (25 C)
Density
1.45 g/cm3 (20 C)
pKa/pKb
8.62 (pKb)
Partition Coefficient
2.03
Heat Of Vaporization
83.01 kJ/mol
Usage
Inhibits platelet aggregation; vasoldilator.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Store at 2 - 8 C. Keep container tightly closed.

Hazards Identification

Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
Skin
Causes irritation. May be harmful if absorbed through the skin.
Eyes
May cause irritation.
Ingestion
Toxic if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
25
EC Safety Phrase
45
UN (DOT)
2811

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Exposure Effects
Target organs/systems: Cardiovascular system. Central nervous system. Blood.

Fire Fighting Measures

Flash Point
286
Fire Fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Transport Information

UN Number
2811
Hazard Class
6.1
Packing Group
III
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