Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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Nimesulide(51803-78-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
Nimesulide
Synonyms
1-(Benzothiazol-2-yl)-1,3-dimethylurea
Aulin
Mesulid
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide
N-(4-Nitro-2-phenoxy-phenyl)methanesulfonamide
Nimesulide
CAS
51803-78-2
Formula
C13H12N2O5S
Molecular Weight
308.31
EINECS
257-431-4
RTECS
PB0970000
RTECS Class
Drug; Reproductive Effector; Human Data
Merck
12,6640
Beilstein/Gmelin
2421175
Beilstein Reference
6-13

Physical and Chemical Properties

Solubility in water
10 mg/L (20 C)
Melting Point
143 - 144
Boiling Point
442
Vapor Pressure
5E-8 (25 C)
Density
1.476 g/cm3
pKa/pKb
8.49 (pKa)
Heat Of Vaporization
69.9 kJ/mol
Usage
Treatment of hyperpyrexia related to respiratory infections.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed.

Hazards Identification

Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Ingestion
May be harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
50/53
EC Safety Phrase
60 61
UN (DOT)
3077

Exposure Controls/Personal Protection

Personal Protection
Protective gloves. Chemical safety goggles.
Respirators
Wear dust mask.
Exposure Effects
Avoid contact and inhalation.
Poison Class
4

Fire Fighting Measures

Flash Point
221
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire Potential
May burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number
3077
Hazard Class
9
Packing Group
III
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