1. Materials information
Use of Z-Pro-OH
Carbobenzoxyproline (L-Cbz-Proline) is an inhibitor of prolidase. Carbobenzoxyproline can be used for prolidase deficiency (PD) research[1]. |
Properties
Articles5
Spectrum
Names
| Name | (2S)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid |
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| Synonym | More Synonyms |
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Z-Pro-OH Biological Activity
| Description | Carbobenzoxyproline (L-Cbz-Proline) is an inhibitor of prolidase. Carbobenzoxyproline can be used for prolidase deficiency (PD) research[1]. |
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| Related Catalog | Research Areas >> Others Signaling Pathways >> Others >> Others |
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| In Vitro | Carbobenzoxyproline (6 mM; 0-10 d; pH=6.0) causes mitochondrial depolarization and increases cellular death by 33% as reported for long-term culture of fibroblasts from prolidase deficiency (PD) patients[1]. Carbobenzoxyproline (0, 1, 3, 6 mM; 1 min; pH=6.0) results fibroblasts prolidase (FBP) hydrolysis, shows linear competitive inhibition[1]. |
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| In Vivo | Carbobenzoxyproline (60 mg/kg; injection; once daily; 3 weeks) serves as in vivo inhibitor of erythrocytes prolidase in mice model[1]. Animal Model: C57Bl/6J mice (4-week-old)[1] Dosage: 60 mg/kg Administration: Injection; once daily for 3 weeks Result: Resulted significant reduction of erythrocytes prolidase activity. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 432.3±45.0 °C at 760 mmHg |
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| Melting Point | 76-78ºC |
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| Molecular Formula | C13H15NO4 |
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| Molecular Weight | 249.262 |
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| Flash Point | 215.3±28.7 °C |
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| Exact Mass | 249.100113 |
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| PSA | 66.84000 |
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| LogP | 1.17 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.582 |
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| Storage condition | 2~8°C |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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