Yohimbine hydrochloride is a white to milky white fine powder with a slight fragrance and bitter taste. It is easily soluble in chloroform, methanol, ethanol, and slightly soluble in water.
The plants come from the dry bark of the African plant Corynante Yohimbe or from the extract of the bark of the West African plant Rubiaceae Chemicalbook family Conan. The pharmacological effect is manifested as an increase in sexual muscle tone and a non-invasive inhibitory effect on urine; Accelerate body energy metabolism and increase energy supply. Clinical single dose therapy is used to treat various types of male impotence and sexual dysfunction. The mechanism of action is to selectively block presynaptic α 2 receptors promote the release of norepinephrine, causing more norepinephrine to be released from the nerve endings of the corpus cavernosum, reducing penile venous reflux, facilitating congestion and erection, and increasing sexual fluid secretion. When applied in small amounts, it can cause swelling of the perineum, stimulate the spinal cord erection center, and cause sexual dysfunction.
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