X-NeuNAc NEW

$36.00 5mg

$55.00 10mg

$98.00 25mg

Min. Order
Purity98.76%
Cas No160369-85-7
Supply Ability10g
Update time2024-11-19

TargetMol Chemicals Inc.

5YR

United States

Since2011-01-07

Address36 Washington Street, Wellesley Hills

show less show more

Chemical Properties

Product Name	X-NeuNAc
CAS No	160369-85-7
EC-No
Min. Order
Purity	98.76%
Supply Ability	10g
Release date	2024/11/19

Product Introduction

Bioactivity

Name	X-NeuNAc
Description	X-NeuNAc (5-Bromo-4-chloro-3-indolyl-alpha-D-N-acetylneuraminic acid sodium salt) is a new chromogenic assay substrate of neuraminidase activity in bacterial expression systems.
In vitro	X-Neu5Ac was hydrolyzed by neuraminidase to release a halogenated product undergoing rapid aerobic oxidation to form the dark blue pigment. Preliminary kinetic studies indicated that X-Neu5Ac was a good and stable substrate for neuraminidase. In addition, X-Neu5Ac would also be hydrolyzed mutant enzymes
In vivo	To visualize extracellular sialidase activity on the membrane surface in the rat brain, acute brain slices were incubated with X-NeuNAc at pH 7.3. After 1h, myelin-abundant regions showed intense fluorescence in the rat brain. Although the hippocampus showed weak fluorescence in the brain, mossy fiber terminals in the hippocampus showed relatively intense fluorescence. In addition, the fluorescence intensities caused by X-NeuNAc was correlated with the sialidase activity. Therefore, staining with X-NeuNAc was specific for sialidase and useful for quantitative analysis of sialidase activities [1].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 60 mg/ml (107.2 mM)
Keywords	X-NeuNAc \| XNeuNAc \| X NeuNAc
Related Compound Libraries	Bioactive Compound Library \| NO PAINS Compound Library \| Bioactive Compounds Library Max \| Anti-Infection Compound Library

show less show more

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.