Chemical Name:Voriconazole
CAS No.: 137234-62-9
Molecular Formula: C16H14F3N5O
Molecular Weight: 349.31
MolecularStructure:
Appearance:White or almost white powder
VoriconazoleTypical Properties
| Item | Specifications | Results |
| Appearance | White or almost white powder | Almost white power |
| Solubility | Very slightly soluble in water;freely soluble in acetone and in methylene chloride | Conform |
| Identification | A.Infrared Absorption spectrum is identical to that of Voriconazole reference standard | Conform |
| B.Enantiomeric purity Solution should be clear and colorless | Conform |
| Appearance of solution | Solution should be clear and colourless | Solution is clear and colourless |
| Water(KF) | Not more than 0.4% | ＜0.1% |
| Sulfated ash | Not more than 0.1% | ＜0.1% |
| Enantiomeric purity | Impurity D not more than 0.2% | 0.01% |
| Impurity E | Not more than 0.10% | 0.02% |
| Related compounds(HPLC) | Impurity A | Not more than 0.15% | ＜0.01% |
| ImpurityB | Not more than 0.15% | ＜0.01% |
| Impurity C | Not more than 0.15% | ＜0.01% |
| Unspecified impurities | Not more than0.10% | ＜0.01% |
| Total impurities | Not more than 0.5% | 0.03% |
| Residual solvents(GC) | Ethanol | Not more than 5000ppm | ＜LOD(LOD=121ppm) |
| Acetone | Not more than 5000ppm | ＜LOD(LOD=15ppm) |
| Assay (HPLC) | 97.5%-102.0% calculated on the anhydrous basis | 99.9% |
| Bacterial endotoxins | Less than 0.2IU/mg | Conform |
| Conclusion | It conforms to all the requirements of EP9.0 |
VoriconazoleUsage
Voriconazole is a broad-spectrum triazole antifungal drug used
primarily to treat progressive, potentially life-threatening infections
in immunodeficient patients.
VoriconazolePackaging and Shipping
Packing: Foil bag , Net weight: 1kg per bag
VoriconazoleStorage
The warehouse is ventilated and dryat low temperatureawayfromfood
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