| Name | Uracil |
| Description | Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions. |
| In vivo | Uracil serves both as a pharmaceutical agent and as a vehicle for drug delivery. In humans and plants, uracil functions is a conformational regulator and coenzyme in various reactions. It also plays a role in the biosynthesis of polysaccharides and the transportation of aldoses. Uracil reacts with fluorine to form 5-fluorouracil, which inhibits RNA polymerase, obstructing RNA synthesis and consequently suppressing the growth of cancer cells. Within the body, uracil binds with ribose and phosphate, aiding insynthesizing enzymes essential for numerous cellular functions. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 18.33 mg/mL (163.53 mM), Sonication is recommended.
H2O : < 1 mg/mL (insoluble or slightly soluble)
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (17.84 mM), Sonication is recommended.
Ethanol : 21 mg/mL (187.35 mM), Sonication is recommended.
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| Keywords | Uracil | RNA | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite |
| Inhibitors Related | Sucrose | Aceglutamide | L-Pyroglutamic acid | Emtricitabine | Levulinic acid | D(+)-Raffinose pentahydrate | D-(+)-Trehalose dihydrate | Glycerol | Thymidine | Gluconate Calcium | Chitosan oligosaccharide | 3-Indoleacetic acid |
| Related Compound Libraries | Marine Natural Product Library | Anti-Tumor Natural Product Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Natural Product Library | Natural Product Library for HTS | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Gut Microbial Metabolite Library |
United States
