Manufacturer Provide Raw Materials CAS13710-19-5 Tolfenamic Acid
Introduction
Product Name: Tolfenamic Acid
Synonyms: Toxamic acid; Tofenamic acid
Appearance:White Crystal Powder
CAS:13710-19-5
MF: C14H12ClNO2
MW:261.7
EINECS: 237-264-3
Melting point: 210-214°C
Boiling Point :405.4±40.0 °C(Predicted)
Density :1.2037 g/mL at 25 °C(lit.)
Solubility :Soluble in water (slightly), acetone (~10 mg/ml), DMSO (52 mg/ml at 25°C), methanol (~10 mg/ml) and ethanol (50 mg/ml).
Storage :Keep in dark place,Inert atmosphere,2-8°C
| Item | Specifications | Results |
| Appearance | White or slightly yellow,crystalline powder | Conform |
| Solubility | Practically insoluble in water,soluble in dimethylformamide,sparingly soluble in ethanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides. | Conform |
| Identification | A. Light absorption:the ration of the absorbance measured at the maximum at 286nm to that maximum at 345nm should be 1.2 to 1.4B. IR absorption spectrophotometry should be conformedC. TLC chromatography(254nm)should be conformed
| 1.2
Conform
Conform |
| Melting point | About 213.0ºC | 212.0-212.7 |
| Related substances | Impurity A<0.1%;impurity B<0.05% | Conform |
| Any other impurity <0.1% |
| Total impurity<0.5% |
| Copper | Not more than 10ppm | Conform |
| Loss on drying | Not more than 0.5% | 0.2% |
| Sulphated ash | Not more than 0.1% | <0.1% |
| Assay (basis on dry) | 99.0%~101.0% | 99.6% |
| Conclusion | The results conforms with BP2009/USP23 standards |
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