Chemical & Physical Properties:
Detail:
CAS:66981-73-5
MF:C21H25ClN2O4S
MW:436.95
EINECS:250-059-3
Melting point:129-131°C
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
Minimum Order Quantity: 100G
Delivery Time: About 4-7 working days
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Superiority:
Yuanhang Bio-pharmaceutical Technology Co.,Ltd achieves millions of US dollars of salesrevenue in recent years. And there are currently over 400 employers, researchers accounting for 37%. We conducted more than 50 kinds of scientific research, and enjoy more than 20 national patents. We have even acquired national invention patent certificate. 5, 184 products of us are almost unique around the world. Our company's various raw chemical materials are of reliable quality, most of which conform to the requirements of FCC, USP and BP, it is mainly sold to pharmacy companies and health care companies abroad. Our target markets comprise of USA, Canada, UK, Brazil, Netherlands, Ireland, New Zealand, Austria, Australia and so on.
Description:
Tianeptine is neuroprotective via multiple neurochemical and cellular mechanisms. In theory, tianeptine's neuroprotective action makes it a potential life-extension drug. When an organism is under stress, or perceives itself under stress, the hypothalamus secretes corticotropin-releasing hormone/factor (CRH/CRF). CRH/CRF in turn increases secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary. ACTH in turn stimulates the release of glucocorticoids from the adrenal cortex. Persistent, uncontrolled physical and psychosocial stress causes excess cortisol secretion from the adrenal glands. Excess cortisol causes dendritic shrinkage in the hippocampus and a contrasting growth of dendrites in the lateral amygdala. These stress-induced changes tend to lower mood; they can cause clinical depression in the genetically vulnerable. Current evidence suggests that tianeptine acts to prevent and even reverse stress-induced neural damage, promoting both neuronal survival and synaptic plasticity.
COA:
| Tests | Specifications | Results |
| Description | White to yellowish powder, very hygroscopic. | Off-white powder, very hygroscopic. |
| Solubility | Freetly soluble In water and methanol and dichloromethane | Complies |
| Identification | (1)By IR, To match with working standard | Complies |
| (2)It gives reaction of sodium | Complies |
| Impurities A | ≤0.1% | Not detected |
| Related compounds | Any impurity ≤0.1% | <0.1% |
| Total impurities ≤0.4% | 0.25% |
| Residual Solvents | Acetidin≤ 0.5% | Not detected |
| Dichloromethane≤ 0.06% | Not detected |
| Methanol≤ 0.3% | Not detected |
| Acetone ≤ 0.5% | Not detected |
| Acetonitrile≤0.041% | Not detected |
| Ethanol≤0.5% | 0.04% |
| N, N-dimethylformamide≤0.088% | Not detected |
| Water | ≤ 5.0% | 1.38% |
| Assay | 99.0%-101.0%(On anhydrous basis) | 99.98% |
| Conclusion | Conform to EP8.0 |
Applicant:
Tianeptine has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in elderly patients and in those following alcohol withdrawal; such patients can be more sensitive to the adverse effects of psychotropic drugs. Recent interesting results indicate anticonvulsant and analgesic activity of tianeptine and its possible interaction with adenosine A1 receptors.
Packaging & Shipping
FAQ
Q: How to start orders or make payments?A: You can send your requirement here on line,or send your purchase order by email to us, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How to confirm the Product Quality before placing orders?A: You can buy samples for some products,and there will be discount for sample, after testing our sample, if all is ok for you, when make bulk order, we can return the sample fee back to you, and you can also send us your requirement for some special item, we can found for you in our local market.
Q: What's your MOQ?A: For the high value product, our MOQ starts from 1g and generally starts from 1kgs. For other low value product, our MOQ starts from 10kg and 100kg.
Q: Is there a discount?A: Different quantity has different discount, for larger quantity, we alway support with better price.
Q: How to contact us? A: You can chat with us by Whatsapp & Skype & wechat Online. You can also choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.
Company Profile
Hebei Ningnan Trade Co., Ltd. located in Shijiazhuang City, Hebei Province, is a large enterprise specializing in production and R & D. Our company has many years of export experience in this industry and professional logistics distribution.
We have many production lines, including industrial chemicals, pharmaceutical chemicals, chemical raw materials, fine chemicals and customized synthetic products.
We have a professional R & D team. Products are widely used in industry, rubber, textile, pharmaceutical and other industries. Products are exported to Europe, America, Southeast Asia and other countries. New and old customers are welcome to negotiate business.
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