Tianeptine (CAS 66981-73-5)
🌟 ChemicalBook Product Introduction
📌 Product Overview
Tianeptine (C₂₁H₂₅ClN₂O₄S), a small-molecule antidepressant, is a serotonin (5-HT) modulator with unique pharmacological activity. Unlike traditional antidepressants, it enhances synaptic serotonin reuptake while reducing anxiety and depressive symptoms without sedative effects. This white crystalline powder (melting point: 129-131°C) is supplied with ≥99% purity (HPLC validated) and is stable under 2-8°C storage. Widely used for mild-to-moderate depression, it also serves as a key intermediate in neuropsychiatric drug development.
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✅ Key Advantages
🔹 Ultra-High Purity
≥99% purity (HPLC/UV validated) | Complies with EP/USP/CP standards.
🔹 Clinically Proven Efficacy
Low cardiac toxicity and minimal side effects compared to SSRIs.
🔹 Long-Term Stability
Stable for 3 years under 2-8°C storage conditions.
🏥 Application Fields
Depression Treatment: Approved for anxiety-associated depressive disorders.
Pharmaceutical R&D: Intermediate for neuropsychiatric drugs and bulk API synthesis.
Chemical Synthesis: Used in custom synthesis for novel therapeutic compounds.
📜 Quality Certifications
Testing Methods: HPLC, NMR, MS, microbial limit testing.
Certifications: GMP, ISO 9001, REACH, and FDA-aligned protocols.
📊 Market Trends
The global antidepressant market is projected to grow at 4.8% CAGR (2025-2030), driven by rising mental health awareness and demand for non-sedative therapies. Asia-Pacific dominates production, with Tianeptine emerging as a cost-effective option for generic formulations.


