Manufacturer Supply High Quality Pure CAS 55297-96-6 Tiamulin
Introduction
Product Name: Tiamulin
CAS Number: 55297-95-5
EINECS Number: 259-580-0
Specification: 99%
Molecular Formula: C28H47NO4S 
Molecular weight:493.74
Expiry Time: 2 Years
Packing: Aluminum Drum(5kg, 20kg), stainless steel drum(100kg,185kg)
Storage: Product should be preserved in tightly closed containers protected from light, heat, and air.
Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms such as streptococci, staphylococci and against mycoplasmas and serpulina (Treponema) hyodysenteriae. A number of Shigella, Klebsiella and E. coli are also quite susceptible to this agent. Some anaerobic species including Bacteroides fragilis and Clostridium perfringens with no exception are sensitive to tiamulin.
Tiamulin acts bacteriostatically. The biochemical basis for the antibacterial action is inhibition of protein synthesis, by binding to 70S ribosomes.
Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratory disease in pigs and poultry; and swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.
| Item | Specification |
| Appearance | White or almost white crystal powder |
| Identification | HPLC: The retention time obtained from the test solution corresponding to that obtained from the standard solution |
| IR: IR of the sample corresponding to that reference standard |
| Color and clarity of solution | The solution should be clear and colorless, and the absorbance at 400nm and 650nm are not greater than 0.150 and 0.030 |
| Specific rotation | +24~28° |
| PH | 3.1~4.1 |
| Loss on drying | ≤ 0.5% |
| Melting point | 143~149°C |
| Fumarate content | 83.7~87.3mg |
| Residue on ignition | ≤ 0.1% |
| Heavy metals | ≤ 0.001% |
| Solvent residue | ≤ 0.5% |
| Chromatographic purity | Any identified impurity ≤ 1.0% |
| Any unidentified impurity ≤ 0.5% |
| Total impurities≤ 2.0% |
| Assay (on dried basis) | 98.0~102.0% |
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