| CAS: | 60-54-8 |
| MF: | C22H24N2O8 |
| MW: | 444.43 |
| EINECS: | 200-481-9 |
| Product Categories: | Peptide Synthesis/Antibiotics;Intermediates & Fine Chemicals;Pharmaceuticals;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics T-ZAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Tetracyclines;Antibiotic Explorer;Inhibitors;60-54-8 |
| Mol File: | 60-54-8.mol |
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| Tetracycline Chemical Properties |
| Melting point | 175-177 °C(lit.) |
| alpha | D25 -257.9° (0.1N HCl); D25 -239° (methanol) |
| Boiling point | 554.44°C (rough estimate) |
| density | 1.3809 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | 95% ethanol: soluble12.5mg/mL |
| form | powder |
| pka | pKa (50% aq DMF): 8.3, 10.2(at 25℃) |
| color | yellow to yellow orange |
| optical activity | [α]25/D -239° in methanol (Specific rotation ) &_& [α]25/D -257.9°, c = 0.1 M HCl mol (Specific rotation ) |
| Water Solubility | Limited solubility in water. Soluble in 1M HCl with heating. |
| Merck | 13,9271 |
| BRN | 2230417 |
| BCS Class | 3 |
| Stability: | Hygroscopic |
| InChIKey | OFVLGDICTFRJMM-WESIUVDSSA-N |
| CAS DataBase Reference | 60-54-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Tetracycline(60-54-8) |
| EPA Substance Registry System | Tetracycline (60-54-8) |
| Tetracycline Usage And Synthesis |
| Description | Tetracycline is an antibiotic that has been utilized in disease management situations in which SmR strains of E. amylovora or P. syringae already exist. However, tetracycline does not appear to be as effective as streptomycin in reducing blossom populations of E. amylovora (17). Additionally, strains of P. syringae with resistance to tetracycline have been isolated from pear orchards in Oregon and Washington (18), suggesting that resistance to this antibiotic will probably develop in orchards where it is applied. |
| Chemical Properties | Crystalline Solid |
| Chemical Properties | Tetracycline trihydrate is a white crystalline substance. |
| Originator | Tetracyn,Pfizer,US,1953 |
| Uses | antibactierial |
| Uses | antibacterial, antiamebic, antirickettsial |
| Uses | Tetracycline is a linear, tetracyclic, broad spectrum antibiotic first prepared chemically by dechlorination of chlortetracycline and subsequently isolated from several Streptomyces species. Tetracycline has broad spectrum antibacterial and antiprotozoan activity, and acts by binding to the 30S and 50S ribosomal subunits blocking protein synthesis. Tetracycline is a pigment and, like many pigments, is degraded by light, oxygen, trace metal ions and pH variations. The purity of tetracycline is often variable, with significant levels of degradation products. |
| Uses | Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis. |
| Uses | Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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