Terbinafine acid is an allylamine dermatological broad-spectrum antifungal drug. It was successfully developed by Swiss Novartis in the 1980s and was first listed in the UK in 1991. It was approved as an OTC drug by the US FDA in 1996, and was listed in the US in the same year. Currently, it is sold in more than 90 countries around the world. It can specifically interfere with the late biodegradation of fungal solid Chemicalbook alcohol, selectively inhibit the activity of fungal squalene epoxidase, and block the squalene epoxidation reaction in the process of fungal cell membrane formation, thereby achieving killing. or inhibit the effect of fungi. It is suitable for the treatment of skin candidiasis, such as tinea pedis, tinea pedis, tinea cruris, tinea corporis and tinea versicolor. It is also the best medicine for the treatment of onychomycosis.
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Density: 1.007g/cm3
Boiling point: 417.9ºC at 760 mmHg
Melting point: 204-208°C
Molecular formula: C21H26ClN
Molecular weight: 327.891
Flash point: 183.7ºC
Exact Mass: 327.175385
PSA: 3.24000
LogP: 5.67930
Appearance: Crystalline powder
Refractive index: 1.586
Storage Conditions: Store in an airtight container in a cool, dry place. Store away from oxidizing agents. Keep away from fire
Stability: stable at normal temperature and pressure, away from oxidants