| CAS: | 2892-51-5 |
| MF: | C4H2O4 |
| MW: | 114.06 |
| EINECS: | 220-761-4 |
| Product Categories: | cyclic compounds;Organic acids;Cyclobutanes & Cyclobutenes;Simple 4-Membered Ring Compounds;Ring Systems |
| Mol File: | 2892-51-5.mol |
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| Squaric acid Chemical Properties |
| Melting point | >300 °C(lit.) |
| Boiling point | 250.96°C |
| density | 1.82 g/cm3 |
| refractive index | 1.5800 (estimate) |
| Fp | 190 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | 20g/l |
| pka | 1.5??(at 25℃) |
| form | Crystalline Powder |
| color | White to beige |
| PH | 1 (1g/l, H2O, 20℃) |
| Water Solubility | 20 g/L (30 ºC) |
| Merck | 14,8769 |
| BRN | 774275 |
| InChIKey | PWEBUXCTKOWPCW-UHFFFAOYSA-N |
| CAS DataBase Reference | 2892-51-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Cyclobutene-1,2-dione, 3,4-dihydroxy-(2892-51-5) |
| EPA Substance Registry System | 3-Cyclobutene-1,2-dione, 3,4-dihydroxy- (2892-51-5) |
| Squaric acid Usage And Synthesis |
| Chemical Properties | Squaric acid (3,4-dihydroxycyclobut-3-ene-1,2-dione), also known as quadratic acid, has the fascinating structure, and is a vinylogous carboxylic acid. The parent compound is a white,crystalline powder which melts at~300℃. It is highly acidic (pKa 1.5 for the first proton and 3.4 for the second) due to resonance stabilization of the anion and exhibits IR resonances indicative of strong hydrogen bonding [2326cm-1 (OH),1818 cm-1 (C=O), and 1639cm-1 (C=C)].The UV absorption spectrum suggests that the acid is essentially completely ionized. Squaric acid is freely soluble in water but has poor solubility in many organic solvents.Solutions give an intense purple color with iron(III) chloride, and are also known to decolorize bromine water, cerium(IV) nitrate, and permanganate solutions.As the carbonyl groups are similar to those of carboxylic acids rather than those of ketones, squaric acid does not react in the phenylhydrazine test.The squarate dianion is thought to be completely symmetrical (unlike squaric acid itself), with all C-C and C-O bond lengths being, respectively, identical, as the negative charges are equally distributed between allthe oxygen atoms.The IR spectrum of dipotassium squarate (dipotassium 3,4-dioxocy-clobut-1-ene-1,2-diolate) differs greatly from that of squaric acid, with the loss of the car-bonyl (C=O) and alkene(C=C) absorptions seen in the protonated form, and supportsthe proposed symmetrical structure. |
| Uses | Squaric acid used as intermediate for squaraine dyes and heterocycles. Squaric acid is an immunotherapy used to treat common warts. This treatment is non-toxic, and easy to use. The treatment activated your immune system to combat the warts and therefore it may cause an allergic reaction , similar to poison oak. This reaction can be managed with a topical cortisone cream. Blistering and lightening of the skin may occur, but rarely.
Squaric acid derivatives – synthetic targets for ring expansion reactions |
| Uses | 3,4-Dihydroxy-3-cyclobutene-1,2-dione is used to produce diethoxy-cyclobutenedione by heating, pharmaceutical intermediates, squarylium dyes, and photoconducting squaraines; The dibutylester is used as a contact sensitizer in the treatment of alopecia and warts. |
| Uses | 3,4-Dihydroxy-3-cyclobutene-1,2-dione can be used:
In fluorescence detection in immunoassays, hybridization assays, enzymatic reactions, and other analytical procedures. To form diffraction quality crystals. To synthesize a squarate dianion, which is used as a building block to create uncharged polymeric networks. These ordered structures are used in catalysis, nonlinear optics, electrical conductivity, molecular recognition, and molecular sieves.
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| Definition | ChEBI: A carbon oxoacid that consists of 1,2-diketocyclobut-3-ene bearing two enolic hydroxy substituents at positions 3 and 4. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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