Manufacturer Provide Medicine Grade Raw Material CAS54-21-7 Sodium Salicylate
Introduction
Product Name: Sodium Salicylate
Other Name :Sdium salicylate;Sodium Salicylate 2-Hydroxybenzoic acid monosodium salt Sodium o-hydroxybenzoate
C.A.S NO. :54-21-7
Assay (%)(HPLC, Basis on drying):99%
Appearance: White Crystal Powder
Molecular formula :C7H5NaO3
Molecular weight :160.1
Melting Point :>300 °C (lit.)
Density:0.32 g/cm3
Storage Condition: Store in cool and dry places ,keep away from strong light
Sodium salicylate is a metabolite of acetylsalicylic acid (sc-217570), and functions by inhibiting NF κ B and reduces oxidative stress. The agent has the ability to protect against neurotoxicity induced by glutamate in rat studies. Along with aspirin (sc-202471), sodium salicylate is an anti-inflammatory compound that binds to and inhibits IKK β. Sodium salicylate has been shown to reduce ATP binding in vitro and in vivo. Sodium Salicylate is an inhibitor of c-Jun and Cox-2 and an activator of p38.
Function
It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID),and induces apoptosis in cancer cells and also necrosis.It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultraviolet radiation and electrons.
Application
In manufacture of aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.
Item | Index | Result |
Appearance | White crystalline powder, soluble in water. It dissolves in dilute acid and alkaline solutions. | Conform |
Identification | a) TLC results | Conform |
b) Color reaction with sulfuric acid | Conform |
c) Color reaction with silver nitrate | Conform |
Ph | 4.5 to 7.0 | 6 |
Specific optical rotation | -203°to -216°° | -206° |
Specific absorbance at 353nm | 290 to 310 | 308 |
308 |
Light-absorbing impurities | a) At 430nm not greater than 0.25 | 0.08 |
b) At 490nm not greater than 0.20 | 0.01 |
Related substances | 4-epioxytetracycline≤ 0.5% | 0.20% |
Tetracycline hydrochloride≤2.0% | 0.30% |
Peak on the tail of the main peak≤2.0% | 1.60% |
Heavy metals | Not more than 50ppm | <50ppm |
Water | 6.0 % to 9.0% | 7.70% |
Sulphated ash | Not more than 0.5% | 0.03% |
Assay | 95.0% -100.5%(C22H24N2O9) based onanhydrous substance | 99.10% |