Chemical Name: Quinine sulfate dihydrate
CAS No.: 6119-70-6
Molecular Formula: C40H48N4O4·H2SO4·2H2O
Chemical Structure:
Molecular weight:782.96
Appearance: White or almost white, crystalline powder or fine, colourless needles
Assay: 99.0-101.0
Quinine sulfate dihydratetypical Properties
| Item | Specifications |
| Appearance | White or almost white, crystalline powder or fine, colourless needles |
| Solubility | Slightly soluble in water sparingly souluble in boiling water and in ethanol |
| PH | 5.7-6.6 |
| Specific optical rotation | -237- -245 |
| Other cinchona alkaloids | ImpurityC ≤10%Any impurity eluted before quinine≤5.0%Anyotherimpurity≤2.5% |
| Loss on drying | 3.0%-5.0% |
| Suiphated ash | ≤0.1% |
| Assay | 99.0-101.0 |
Quinine sulfate dihydrateUsage
Quinine sulfate is a quinoline derivative that binds to the DNA of
Plasmodium and forms a complex that inhibits DNA replication and RNA
transcription, thereby inhibiting protozoal protein synthesis, which is
weaker than chloroquine. It is suitable for falciparum malaria caused by
chloroquine and multi-drug resistant strains. It can also be used to
treat vivax malaria. For asthma, atrial fibrillation and other serious
heart conditions, patients with glucose-6-phosphate dehydrogenase
deficiency and women’s menstrual period should be used with caution.
Pregnant women are banned.
Quinine sulfate dihydratePackaging and Shipping
Packing: 25kg/drum
Delivery: have the stock
5-Acetyl-2,4-dimethylthiazoleStorage
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
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