Pyrazinamide - Product Introduction
Definition
Pyrazinamide is an antibiotic used in the treatment of tuberculosis (TB). It is typically included in combination therapy with other anti-TB drugs to enhance treatment effectiveness.
Functions
· Antitubercular: Targets Mycobacterium tuberculosis by disrupting bacterial cell metabolism, which inhibits the bacteria's ability to survive in acidic environments.
· Sterilizing Agent: Helps eliminate dormant or semi-dormant TB bacteria in tissues, particularly in the lungs.
· Enhances Combination Therapy: Often used alongside other TB drugs like rifampicin, isoniazid, and ethambutol to improve cure rates.
Applications
· Pharmaceuticals: Essential in the treatment regimen for tuberculosis, often used in the intensive phase of TB treatment.
· Combination Therapy: Commonly combined with other anti-TB drugs to form multi-drug regimens for both active and latent tuberculosis.
· Research: Investigated for its role in addressing drug-resistant TB strains and improving treatment protocols.
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