Use of Procaine hydrochloride
Procaine Hydrochloride is a local anesthetic drug of the amino ester group.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale [3].
| Boiling Point | 195-196°C 17mm |
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| Melting Point | 155-156 °C(lit.) |
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| Molecular Formula | C13H21ClN2O2 |
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| Molecular Weight | 272.771 |
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| Flash Point | 195-196°C/17mm |
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| Exact Mass | 272.129150 |
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| PSA | 55.56000 |
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| LogP | 3.15060 |
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| Stability | Stable. Incompatible with strong oxidizing agents. |
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| Water Solubility | soluble |
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