Amicaine is an amide local anesthetic with similar anesthetic intensity and speed to lidocaine, but the duration is longer and the effect on vasodilation is weaker. Toxicity is lower than Ridoka. Clinical use for local anesthesia, especially for patients who avoid epinephrine.
Chemical properties Acicular crystal. Melting point 37-38℃, boiling point 159-162℃ (0.133kPa), refractive index (nD20) 1.5299. Its hydrochloride ([1786-81-8]) is a white crystalline powder. Melting point 167-168℃. Soluble in water and Chemicalbook ethanol, slightly soluble in chloroform. Taste sour bitter, odorless. Uses as a local anesthetic. The drug effect is better than procaine, the local anesthetic intensity and speed are similar to lidocaine, but the action time is longer, the toxicity is less, because the metabolism is fast, the accumulation is also smaller. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia
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