Perfluoronaphthalene is the earliest fluorocarbon product used in medicine, safe, non-toxic, and stable in nature. It has been clinically used to treat acute respiratory distress syndrome. Meanwhile, perfluoronaphthalene is also used as a blood substitute and ophthalmic heavy water in vitreoretinal surgery. In the field of cosmetics, perfluoronaphthalene is also used as a skin conditioner and solvent. Perfluoronaphthalene has been extensively studied clinically, with a wide range of applications and high reliability.