Paliperidone

Product Name:    Paliperidone

Synonyms:    Paliperidone (Invega);3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-Methyl-;Risperidone EP IMpurity C;Paliperidone 9-Hydroxyrisperidone;9-Hydroxyrisperidone solution;Risperidone Impurity 3(Risperidone EP Impurity C);Racemic Paliperidone;Paliperidone (9-Hydroxy Risperidone, Risperidone EP Impurity C)

CAS:    144598-75-4

MF:    C23H27FN4O3

MW:    426.48

EINECS:    620-493-1

Product Categories:    Other APIs;Invega, INVEGA Sustenna, 9-hydroxyrisperidone;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Heterocycles;144598-75-4

Paliperidone, the C-9 hydroxylated active metabolite of the antipsychotic agent risperidone, is the newest atypical antipsychotic to join the market following the introductions of olanzapine (ZyprexaTM), risperidone (RisperdalTM), quetiapine(SeroquelTM), and ziprasidone (GeodonTM). Compared to its parent, paliperidone has improved PK properties and a reduced potential for drug interactions. In terms of receptor affinity, the two drugs are equipotent.