Paeoniflorin is a chemical compound. It is one of the major constituents of a herbal medicine derived from Paeonia lactiflora. It can also be isolated from the fresh water fern Salvinia molesta.
In Paeonia, it can form new compounds with addition of phenolic substituents. Paeoniflorin has antiandrogenic properties. Paeoniflorin inhibits the production of testosterone and promotes the activity of aromatase - the enzyme that converts testosterone into estrogen.
| Name | Paeoniflorin | EINECS | 245-476-2 |
| CAS No. | 23180-57-6 | Density | 1.63 g/cm3 |
| PSA | 164.37000 | LogP | -1.35750 |
| Solubility | N/A | Melting Point | approximate 124℃ (dec.)
|
| Formula | C23H28O11 | Boiling Point | 683.3 °C at 760 mmHg |
| Molecular Weight | 480.469 | Flash Point | 235.9 °C |
| Transport Information | N/A | Appearance | White fine powder |
Density: 1.63g /cm3
Boiling point: 683.3ºC at 760 mmHg
Flash point: 235.9ºC
Refractive index: 1.649
Vapor pressure: 1.07E-19mmHg at 25°C
Usage
1. Cardiovascular effects: dilate coronary arteries, increase coronary flow, combat acute myocardial ischemia, inhibit platelet aggregation and reduce blood pressure.
2. Analgesia and sedation: intraperitoneal injection of mice has significant analgesic effect, which can prolong the sleep time of mice with cyclohexenobarbital sodium, and has antagonistic effect on convulsion caused by pentamethylenetetrazole.
3. Anti-inflammatory and anti-ulcer: The foot and ankle swelling of rats caused by diagonalenin and dextran can be inhibited, and the stress ulcer of rats can be prevented and the gastric secretion can be inhibited.
4. Antipyretic: It has a lowering effect on normal body temperature of mice and antipyretic effect on artificially heated mice.
5. Spasmolysis: inhibition of isolated intestinal tube and gastric motility in rats and guinea pigs, and inhibition of uterine smooth muscle in rats, and antagonism of uterine contractions caused by oxytocin.
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