| Name | Oxantel Pamoate |
| Description | Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent. |
| In vivo | The efficacy of the veterinary drug Oxantel pamoate against Trichuris muris, Ancylostoma ceylanicum, and Necator americanus was evaluated, revealing an ED50s of 4.7 mg/kg for T. muris in mice. When combined with pyrantel pamoate, Oxantel pamoate showed an antagonistic interaction (CI=2.53). Similarly, combinations with Levamisole, Albendazole, or Ivermectin, based on their ED50s, also demonstrated antagonistic effects (CIs of 1.27, 1.90, and 1.27, respectively). Conversely, a combination with mebendazole exhibited a highly synergistic effect (CI=0.15) against T. muris infection. At a dosage of 10 mg/kg, Oxantel pamoate was ineffective against A. ceylanicum and N. americanus[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 60 mg/mL (99.23 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.31 mM), Sonication is recommended.
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| Keywords | Parasite | Oxantel Pamoate | Oxantel | Inhibitor | inhibit | Antiparasitic |
| Inhibitors Related | Picaridin | Kaempferol | Kojic acid | Urethane | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Diethyltoluamide | Artemisinin | DL-Methionine |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Pediatric Drug Library | Approved Drug Library | Drug Repurposing Compound Library | NO PAINS Compound Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
United States
