Nadifloxacin (CAS 124858-35-1)
🌟 ChemicalBook Product Introduction
📌 Product Overview
Nadifloxacin is a broad-spectrum fluoroquinolone antibiotic with the molecular formula C19H21FN2O4. It effectively inhibits bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication and synthesis, making it ideal for treating skin infections such as acne vulgaris, folliculitis, and impetigo. Available as a white to off-white crystalline powder, it offers a purity of ≥98% (HPLC verified) and remains stable under recommended storage conditions (0-8°C or -20°C).
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✅ Key Advantages
🔹 High Purity & Stability
Purity ≥98% (HPLC/UV verified) | Stable for long-term storage at -20°C or 0-8°C.
🔹 Broad-Spectrum Antibacterial Action
Targets Gram-positive/negative bacteria and anaerobic strains | IC50 <0.1 μg/mL against Propionibacterium acnes.
🔹 Topical Safety & Efficacy
Minimizes systemic side effects | Clinically proven to reduce inflammatory acne lesions.
🔹 Global Compliance
Meets EP/CP/USP standards | Produced in GMP-certified facilities.
🏥 Application Fields
Dermatology: Treatment of acne vulgaris, folliculitis, and impetigo.
Topical Formulations: Key ingredient in creams, gels, and ointments for bacterial skin infections.
Research: Antibacterial mechanism studies and formulation development.
📜 Quality Certifications
Testing Methods: HPLC, NMR, MS, and microbial limit testing.
Certifications: ISO 9001, GMP compliance, and FDA-aligned quality systems.
📊 Market Trends
The global acne treatment market is projected to grow at 4.2% CAGR (2025-2030), driven by rising antibiotic-resistant skin infections. Nadifloxacin’s efficacy against C. acnes positions it as a critical component in topical antibiotic demand, particularly in Asia-Pacific regions.
China
