N-Iodosuccinimide
Product Name N-Iodosuccinimide
CAS 516-12-1
MF C4H4INO2
MW 224.98
EINECS 208-221-6
MOL File 516-12-1.mol
Chemical Properties
Melting point 202-206 °C(lit.)
Boiling point 249.6±23.0 °C(Predicted)
Density 2,245 g/cm3
storage temp. 2-8°C
solubility Soluble in dioxanee, tetrahydrfuran and acetonitrilee. Insoluble in ether and carbon tetrachloridee.
form Crystalline Powder
pka -2.57±0.20(Predicted)
color White-yellow to brown
Water Solubility decomposes
Sensitive Moisture Sensitive
Usage And Synthesis
Chemical Properties
white-yellow to brown crystalline powder
Uses
N-Iodosuccinimide is a iodo substituted succinimide that is used as an iodinating agent in chemical synthesis.
Uses
Iodination of ketones and aldehydes.
Highly substituted iodobenzenes prepared via an efficient 2-step process from 1,6-diynes.
Used with TFA to chemoselectively hydrolyze thioglycosides to 1-hydroxyglycosides.
Synthesis of vinyl sulfones from olefins and benzenesulfinic acid.
Uses
N-Iodosuccinimide is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. It is also used to hydrolyze thioglycosides to 1-hydroxyglycosides with triluoroacetic acid. It is involved in the preparation of iodobenzene from 1,6-diynes. Further, it acts as an iodinating agent in chemical synthesis.
Hebei Jingbo New Material Technology Co., Ltd. was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.Our company has strong technical strength, advanced equipment, strict quality management system and high-quality after-sales service, adhers to the "customer first and forge ahead" business philosophy and insists on integrity as the company's survival.
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