Chemical Name:Moxidectin
CAS No.:113507-06-5
Molecular Formula: 113507-06-5
Molecular Weight: 639.825
MolecularStructure:
Appearance: White or pale yellow amorphous powder
Moxidectin Typical Properties
Item | Specifications | Results |
Appearance | White or pale yellow amorphous powder | White amorphous powder |
Identification | IR spectrum of sample corresponds to that of reference substance | Comply |
The retention time of the major peak of the sample solution
corresponds to that of the standard solution, as obtained in the assay | Comply |
Water | ≤1.3 % | 0.6 % |
Residue on ignition | ≤0.2 % | 0.04 % |
Heavy Metals | ≤20 ppm | < 20 ppm |
Assay( anhydrous basis ) | 92.0 % – 102.0 % | 98.2 % |
Organic impurities | Early-eluting impurities | Moxidectin butenyl analog ( A ) ≤1.5 % | 0.1 % |
5’-Demethyl moxidectin( B ) ≤0.5% | 0.2 % |
Moxidectin pentenly analog ( C ) ≤1.5 % | 0.4 % |
Moxidectin 17a-epimer ( D ) ≤2.5% | 0.2 % |
Sum of moxidectin 19-S-17a-ene and moxidectin ethyl isomers (E F ) ≤1.7 % | 0.3 % |
Milbeycin B analog ( moxidectin open ring ) \( G ) ≤1.5 % | Not detected |
Any other individual impurity eluting before milbmycin B analog ( moxidectin open ring ) ≤0.5 % | 0.2 % |
Late-eluting impurities | Moxidectin deoxydienea and 4’-Methylthiomethoxymoxidectin ( H I ) ≤1.0 % | Not detected |
20b-Methylthiomoxidectin( J ) ≤0.5 % | Not detected |
20-Nitrobenzoylmoxidectin( K ) ≤0.5 % | Not detected |
Any other individual impurity eluting after the milbeycin B analog (moxidectin open ring ) ≤0.5 % | Not detected |
Total organic impurities | ≤7.0 % | 1.7 % |
Solvent residue | Methanol ≤3000 ppm | Not detected |
Methylene chloride ≤300 ppm | Not detected |
Isopropyl acetate ≤5000 ppm | Not detected |
N-heptane ≤3000 ppm | 72 ppm |
BHT | 0.3 % – 0.6 % | 0.49 % |
Conclusion | The product complies with the specification ( USP ) |
Storage | Preserve in well-closed, light-resistant containers, and store in room temperature . |
Moxidectin Usage
1. Moxidectin can be used as a veterinary anthelmintic.
2. As a new generation of deworming drugs, moxidectine can
effectively kill nematodes and surface parasites.It is quite safeto
animals.
3. It is superior to ivermectin in dosage, formulation development, drug resistance and drug distribution in vivo.
Moxidectin Packaging and Shipping
Packing: 25kg/drum
Moxidectin Storage
Stored in a cool dry and sealed container away from children
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