Chemical Name:Milbemycin Oxime
CAS No.:129496-10-2
Molecular Formula:2C32H45NO7.2C31H43NO7
Molecular Weight:2194.78
MolecularStructure:
Appearance: White or light yellow amorphous powder
Milbemycin Oxime Typical Properties
| Item | Specifications | Results |
| Appearance | White orlight yellow amorphous powder | White amorphous powder |
| Identification | IR spectrum of sample corresponds to that of reference substance | Comply |
| The retention time of the major peak of the sample
solution corresponds to that of the standard solution, as obtained in
the assay | Comply |
| Water | ≤3.0 % | 1.0 % |
| Residue on ignition | ≤0.5 % | 0.1 % |
| Assay | ( Sum of Milbemycin A4 oxime and Milbemycin A3 oxime) : 95.0%-102.0 on the anhydrous basis . | 98.1 % |
| Ratio of Milbemycin A4 oxime ≥ 0.75 | 0.94 |
| Ratio of Milbemycin A3 oxime ≥ 0.25 | 0.06 |
| Organic impuritis | Impurity a: 11’DesmethylMilbemycin A4 oxime ≤0.7 % | 0.06 % |
| Impurity b: (20’R)-Hydroxymilbemycin A4keto form ≤0.5% | 0.1 % |
| Impurity c: Milbemycin A4 keto form ≤0.7 % | 0.4 % |
| Impurity d: Milbemycin D oxime ≤3.0% | 0.2 % |
| Any other individual impurity ≤0.5 % | 0.2 % |
| Total impurities ( excluding impurity d ) ≤3.5 % | 1.3 % |
| Reporting threshold: 0.10 % | 0.2 % |
| Solvent residue | Trichloromethane ≤60 ppm | Not detected |
| N-Heptane ≤5000 ppm | 2 ppm |
| Ethanol ≤5000 ppm | 24 ppm |
| Conclusion | The product complies with the specification ( USP ) |
| Storage | Preserve in tight containers, and store at room temperature , protected from light . |
Milbemycin Oxime Usage
1.It is a special medicine for preventing and treating parasites in dogs and cats.
2.It can effectively control heartworms and prevent endoparasites
such as hookworms, roundworms, whipworms and aphids, as well as hair
follicles, mites, ticks, fleas, etc.
Milbemycin Oxime Packaging and Shipping
Packing: 25kg/ drum
Milbemycin Oxime Storage
Stored in a cool dry and sealed container away from children
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