Description: Minoxidil is an oral drug used clinically to lower blood pressure. It is also called long-term pressure, piperidine diamine, antihypertensive, and Minlexedine. It is a potassium channel opener that can directly relax vascular smooth muscle and has a strong dilation effect on arterioles, which can reduce peripheral resistance, dilate blood vessels, and reduce blood pressure, but has no effect on capacitance vessels, so it can promote venous return. At the same time, due to reflex regulation and positive frequency effects, cardiac output and heart rate can be increased, but postural hypotension is not caused. It is clinically used for the treatment of refractory hypertension and renal hypertension. It can also be used for severe hypertension that is not effective with other antihypertensive drugs, but it needs to be used in combination with diuretics to avoid water and sodium retention. It can be used in combination with beta-receptor blockers to increase its efficacy and reduce adverse reactions. Long-term use of minoxidil may have a side effect, that is, the body hair may increase slightly with the continued use of the drug, such as arm hair. But it is generally within an acceptable range.