| Name | Methyl cinnamate |
| Description | Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects. |
| In vitro | At 1-3000 μmol/L, the E-isomer of methyl cinnamate (E-MC) concentration-dependently relaxed endothelium-intact aortic preparations that had been precontracted with phenylephrine (PHE; 1 μmol/L), with an IC50 value (geometric mean) of 877.6 μmol/L (95% confidence interval (CI) 784.1-982.2 μmol/L). Over the concentration range 1-3000 μmol/L, E-MC relaxed K(+) -induced contractions in mesenteric artery preparations (IC50 314.5 μmol/L; 95% CI 141.9-697.0 μmol/L) with greater potency than in aortic preparations (IC50 1144.7 μmol/L; 95% CI 823.2-1591.9 μmol/L). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : Insoluble
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (12.33 mM), Sonication is recommended.
DMSO : 50 mg/mL (308.28 mM), Sonication is recommended.
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| Keywords | Tyrosinase | SREBP-1 | preadipocytes | PPARγ | natural | Methyl cinnamate | Methyl 3-phenylpropenoate | Inhibitor | inhibit | flavor | cells | CaMKK2 | C/EBPα | Bacterial | antimicrobial | AMPK | AMP-activated protein kinase | activation | 3T3-L1 |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Ethyl linoleate | Dimethyl sulfoxide | Sodium diacetate | Chitosan oligosaccharide | BES |
| Related Compound Libraries | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Neuroprotective Compound Library | Inhibitor Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Anti-infective Natural Product Library | Flavor Natural Product library | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
United States
