1. Materials information
Names
Name | menaquinone-7 |
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Synonym | More Synonyms |
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Vitamin K2(35) Biological Activity
Description | Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3]. |
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Related Catalog | Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others |
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References | [1]. Thijssen, H H., et al., 1994. Vitamin K distribution in rat tissues: dietary phylloquinone is a source of tissue menaquinone-4. The British journal of nutrition. 72(3): 415-25. [2]. Conly, J M., et al., 1994. The contribution of vitamin K2 (menaquinones) produced by the intestinal microflora to human nutritional requirements for vitamin K. The American journal of gastroenterology. 89(6): 915-23. [3]. Peeters FECM, et al. Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients. 2018 Mar 21;10(4). pii: E386. |
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Chemical & Physical Properties
Density | 0.961 |
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Boiling Point | 720.1±60.0 °C at 760 mmHg |
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Melting Point | 54ºC |
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Molecular Formula | C46H64O2 |
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Molecular Weight | 648.999 |
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Flash Point | 254.9±29.9 °C |
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Exact Mass | 648.490601 |
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PSA | 34.14000 |
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LogP | 17.05 |
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Vapour Pressure | 0.0±2.3 mmHg at 25°C |
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Index of Refraction | 1.532 |
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Storage condition | -20C |
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Safety Information
RIDADR | NONH for all modes of transport |
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Precursor & DownStream
Precursor 6 | Previous 1/2 Next |
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CAS#:106-28-5 (2E,6E)-Farnesol CAS#:24163-93-7 (E,E)-3,7,11-tr... CAS#:104423-44-1 (2E,6E,10E)-12-... CAS#:40266-21-5 (3,7,11-trimeth...
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2. Packaging of materials
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