Description of Melatonin from Watson Biotechnology Co., Ltd
Basic Information of Melatonin |
Product Name | Melatonin |
CAS NO. | 73-31-4 |
Apperance | White powder |
Assay | 99% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Watson |
Specifications(COA) of Melatonin Powder CAS 73-31-4
Items | Specifications | Results |
Identification | IR,UV,HPLC | Conform |
Chlorid and Sulfate | ≤0.02% | ﹤0.02% |
Loss on drying | ≤1.0% | 0.06% |
Residue on ignition | ≤0.1% | 0.06% |
Heavy metal | Pb ≤1ppm | ﹤1ppm |
As ≤1.5ppm | ﹤1.5ppm |
Hg ≤1.5ppm | ﹤1.5ppm |
Cd ≤0.5ppm | ﹤0.5ppm |
Impurities | Individual impurity≤0.1% | 0.039% |
Total impurity≤1.0% | 0.19% |
Assay(on the dried basis) | 98.5%~101.5% | 99.59% |
Conclusion | The product conforms to the standard of USP42. |
Melatonin (C₁₃H₁₆N₂O₂) is a naturally occurring hormone primarily secreted by the pineal gland in the brain. It regulates the sleep-wake cycle (circadian rhythm) by responding to darkness, promoting drowsiness and lowering body temperature.
Key Functions & Uses:
1. Sleep Regulation: Treats insomnia, jet lag, and shift-work disorders.
2. Antioxidant: Neutralizes free radicals, potentially slowing cellular aging.
3. Immune Support: Modulates immune responses and reduces inflammation.
4. Oncology: Studied for adjunct cancer therapy due to its anti-tumor properties.
Available as supplements, melatonin is widely used for sleep disorders but should be taken under guidance to avoid disrupting natural production.
Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone produced by the pineal gland, primarily known for regulating the sleep-wake cycle (circadian rhythm). Its applications span medical, therapeutic, and even agricultural fields due to its antioxidant, anti-inflammatory, and chronobiotic properties.
1. Sleep Disorders
Insomnia: Short-term use improves sleep onset and quality (especially in elderly or jet lag sufferers).
Jet Lag & Shift Work: Resets circadian rhythms after rapid time-zone changes or irregular schedules.
-Delayed Sleep-Wake Phase Disorder (DSWPD): Helps realign abnormal sleep patterns.
2. Neuroprotection & Antioxidant Effects
- Neurodegenerative Diseases: Potential adjunct therapy for Alzheimer’s and Parkinson’s (reduces oxidative stress).
Stroke Recovery: Animal studies show reduced brain damage post-ischemia.
3. Immune Modulation
Inflammation Control: Suppresses pro-inflammatory cytokines (e.g., in sepsis or COVID-19 research).
Autoimmune Diseases: May alleviate symptoms of rheumatoid arthritis or multiple sclerosis.
4. Oncology Support
Cancer Therapy: Enhances efficacy of chemo/radiotherapy while reducing side effects (e.g., breast/prostate cancer).
Prevention: Antioxidant properties may lower cancer risk (limited evidence).
5. Mental Health
Depression/Anxiety: Seasonal Affective Disorder (SAD) and mood regulation (linked to circadian disruption).
6. Other Uses
GI Health: Irritable Bowel Syndrome (IBS) via gut microbiota modulation.
Agriculture: Improves crop stress resistance and livestock reproduction.
Safety Notes
Dosage: Typically 0.5–5 mg/day; higher doses may cause grogginess or nightmares.
Contraindications: Autoimmune diseases, pregnancy, or concurrent immunosuppressants (consult a doctor).
Melatonin’s low toxicity and multi-target effects make it a promising molecule for broader therapeutic exploration.
FAQ From Watson Biotechnology Co., Ltd |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
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Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
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Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
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Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
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Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
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Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Founded in 2006 and headquartered in Wuhan, Hubei, China, Watson Biotechnology Co., Ltd is a leading manufacturing powerhouse specializing in the production of Active Pharmaceutical Ingredients (APIs) and Intermediates, Food and Feed Additives, Agricultural and Aquaculture chemicals, and Fine Chemicals. As a dedicated factory, our operations are driven by a commitment to excellence and innovation, ensuring that our products meet the highest standards of quality and compliance.
With a robust team of over 100 skilled professionals, Watson Biotechnology has established itself as a trusted name in the industry. Our products are meticulously crafted to align with international standards such as USP (United States Pharmacopeia), EP (European Pharmacopoeia), and BP (British Pharmacopoeia), guaranteeing reliability and efficacy.
At Watson Biotechnology, we pride ourselves on our cutting-edge facilities and state-of-the-art technology, which enable us to deliver superior products that cater to a diverse range of needs across various sectors. Our dedication to continuous improvement and customer satisfaction drives us to maintain stringent quality control processes and foster an environment of innovation and growth.
Watson Biotechnology Co., Ltd is a professional manufacturer which provide Melatonin with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Melatonin.
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