English name: Melanotan 1
CAS number: 75921-69-6
Molecular formula: C78H111N21O19
Molecular weight: 1646.85
EINECS Number: 211-519-9
Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.
FAQ
Q1:Can i get free sample ?
A: Yes, most product we can send you small free sample, you just need to pay the shipping cost .
Q2:Which payment method you accept?
A: We accept bank transfer,western union, money gram,bitcoin, USDT,Credit card etc. and more bigger order we accept L/C at sight
Q3: Can i get tracking number after shipment ? and how long does the shipping take?
A: After shipment we will offer you tracking and tell you the website to track the package, usually the shipping time is 3-
7days,but for some customers have no ability to declare customs, we use special line route to ship the package, it will take 10-
12days to arrive,make sure 100% delivery
Q4: How can you guarantee the quality ?
A: All products we can supply you test report &you can also send our product to the third party to do test, if it is fake,we will
full refund you.
Our Advantage
1. Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years, our products have exported
to Germany, Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our
customers, we had Established long friendly relations of cooperation.
2. Great quality, purity and favourable.
Good quality is one of our secret success, welcome order the samples, MOQ just 5 grams.
3. Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
We have special way could ship 0.01kg to 3.5kg products a time. We offer melting powder into liquid service. And ship the liquid
in special bottles.
4. Good after-sales service.
Tell me the package update, and will try best solve when customer encountered various problems.