Mannitol is a good diuretic in medicine, reducing intracranial pressure, intraocular pressure and treatment of kidney drugs, dehydrating agents, sugar substitutes, excipients used as tablets, and solid and liquid diluents. As a high-permeability antihypertensive drug, mannitol injection is a commonly used drug for clinical rescue, especially for the rescue of brain diseases. It has the characteristics of quick blood pressure reduction and accurate curative effect required for reducing intracranial pressure drugs. As a vehicle excipient, mannitol has no hygroscopicity, fast drying, good chemical stability, and has the characteristics of refreshing and granulating, and is used for anticancer drugs, antibacterial drugs, antihistamines and vitamins. Part of the tablet. In addition, it is also used for chewing tablets such as hangover medicines and oral fresheners.
| Item | Standard |
| Appearance | White crystalline powder |
| Assay (%) | 98.0-102.0 |
| Loss on drying (%) | ≤0.5 |
| Specific rotation | +23~+25° |
| Heavy metal (Pb) (%) | <10ppm |
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| Nickel (%) | ≤ 0.30 |
| Oxalate (%) | <0.02 |
| Sulfate (SO4) (%) | ≤0.01 |
| Chloride (Cl) (%) | ≤0.003 |
| Melting point ( ºC) | 166-170 °C |
| Acidity | Conform |
| Residue on ignition (%) | <0.1 |
| Storage | in the shade |
| Packing | 25kg/drum |
China
