| Name: | Lopinavir |
| CAS No.: | 192725-17-0 |
| MF: | C37H48N4O5 |
| Appearance: | White Powder |
| purity | >99% |
| Molecular weight | 628.81 |
| EINECS Number | 200-001-8 |
| Items | Standards | Results |
| Appearance | White or off-white solid powder | Complies |
| Identification | By IR | Complies |
| By HPLC | Complies |
| Solubility | Soluble in DMF, sparingly soluble in THF,insoluble in water | Complies |
| Polymorphic Form | Polymorphic form 1 | Complies |
| Melting Point | 211ºC~216ºC | 212.8ºC~214.9ºC |
| Water Content | ≤ 0.50% | 0.10% |
| Heavy Metals | ≤ 20ppm | Complies |
| Residue on Ignition | ≤ 0.20% | 0.09% |
| Related Substance | Any single impurity: ≤0.10% | 0.06% |
| Total Impurities: ≤1.00% | 0.16% |
| Assay (on the anhydrous basis) | 98.0%~102.0% | 99.94% |
| Particle Size | D90: ≤100µm | Complies |
HIV Protease Inhibition: Lopinavir targets and inhibits the HIV-1 protease, preventing the cleavage of the viral polyprotein precursor into functional viral proteins. This leads to the production of non-infectious virions, effectively blocking the viral replication cycle.
Combination Therapy Synergy: When used in combination with ritonavir, lopinavir exhibits enhanced bioavailability and antiviral activity, providing a more potent therapeutic effect against HIV.
Additional Enzymatic Inhibition: In addition to its primary action on HIV protease, lopinavir also has inhibitory effects on other enzymes, such as ZMPSTE24 (zinc metallopeptidase STE24), although its therapeutic significance in this regard may vary.
Company Profile
Hebei Zhuanglai Chemical Trading Co.,Ltd. is a foreign trading company, specializing in developing and producing Chemical raw materials, pharmaceutical intermediates.It has its own factory, which procures itself a competitive edge in market.
For many years, our company has won many clients' support and trust because it always strives to make high-quality merchandise with favorable price. It commits itself to satisfy every clients, in return, our customer show great confidence and respect for our company. In spite of so many loyal customers won these years, Hegui keeps modest all the time and strives to better itself from every aspect.
We are looking forward to cooperating with you and having a win-win relationship with you. Please rest assured that we will satisfy you. Just feel free to contact me.
Packing & Shipping
FAQ
Q1. What is your delivery term and delivery period?
We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. Competitive price with ready stocks; by Air within 7days, by sea within 14 days shipping after .
Q2. What's your main markets?
South&North America, Europe, Asia, Africa etc. Top customers among more than 80 countries; 30 years history; One-stop supplier.
Q3. What is the payment term?
Normally we advise customers use Trade Assurance(is a free payment protection service for buyers is offered by Alibaba group), and we also receive T/T, Western Union or L/C.
Q4. Will you supply samples for test the quality?
We'd like to offer our customers samples for the quality evaluation for most products to develop business.
China
