| Name | Kaempferol 3-sophoroside-7-glucoside |
| Description | Kaempferol 3-sophoroside-7-glucoside, a flavonoid found in Lei leaves, exhibits bioactive properties including antioxidant and anti-obesity activities. |
| In vitro | The roasting process followed by a 30% EtOH extraction tended to enhance the content of kaempferol-3-sophoroside-7-glucoside. It effectively inhibited pancreatic lipase activity by 62.50 ± 4.81%, which was approximately 1.71 percentage points higher than that of the dried-nonroasted LCL extract (60.79 ± 3.75%). Its bioaccessible fraction obtained from in vitro digestion significantly and dose-dependently reduced intracellular lipid accumulation by adipocyte 3T3-L1 compared with a 30% EtOH extraction. At a concentration of 200 μg/mL, it inhibited lipid accumulation up to 29.55% in 3T3-L1 cells, which indicated that human digestive enzymes converted kaempferol-3-sophoroside-7-glucoside to kaempferol metabolites that have anti-obesity effects.[1] |
| In vivo | Apigenin 7-O-β-D-glucopyranoside and kaempferol-3-sophoroside-7-glucoside, among others, were the main chemical constituents of Pteris wallichiana J. Agardh extract (PEW). In LPS-induced Raw264.7 inflammation and DSS-induced mouse colon UC, PEW pretreatment can significantly reduce the expressions of inflammatory cytokines in vitro and in vivo. In DSS-induced UC mice, PWE can improve the abnormal pathological tissue damage by inhibiting oxidative stress and inflammation-related signaling pathways, and improve the intestinal barrier function.[1] |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Kaempferol 3 sophoroside 7 glucoside | Kaempferol 3-sophoroside-7-glucoside | Kaempferol 3sophoroside7glucoside |
| Inhibitors Related | Thiamine monochloride | 2-Heptanol | Butylated hydroxytoluene | Propyl gallate | L-Tartaric acid | Neohesperidin | Sulbutiamine | m-Coumaric acid | L-Cystine | Chrysin |
| Related Compound Libraries | Rare Natural Product Library | Natural Product Library for HTS |
United States
